Chronic bronchitis is a type of chronic obstructive pulmonary disease (COPD) that is characterized by excessive bronchial mucus secretion and a productive cough that usually lasts three months or longer in two consecutive years. Abnormalities associated with chronic bronchitis are thickened bronchial walls, mucosal inflammation in the walls and airways, and hypertrophied and hyperplastic mucus glands (Arcangelo & Peterson, 2013). The recommended drug treatment for controlling chronic bronchitis is divided into three lines (Arcangelo & Peterson, 2013). First, aminopenicilins, such as ampicillin and amoxicillin, are usually sufficient for simple chronic bronchitis cases. Second, in complicated chronic bronchitis, second-generation or third-generation ...
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