Klebsiella Ozaenae Bacteria
A brief background of Klebsiella ozaenae bacteria; the generic name of Klebsiella is a member of the family of Enterobacteriaceae. Klebsiellae take the shape of the rod and are non-motile but have a polysaccharide capsule. What is the primary work of the encrypting capsule? Firstly, the capsule is responsible for the large appearance for the orgasm. It also provides resistance and immunity to the bacteria against the immune system and the defense mechanism of the host’s body (Goldstein, Lewis, Martin & Edelstein, 1978, p. 415). Members of the genus of Klebsiella typically express types of antigens on their cell surfaces. The antigens include lipopolysaccharide (O antigen) and polysaccharide (K antigen). It is important to note that these antigens contribute heavily to pathogenicity.
The patient I examined exhibit some distinct symptoms rare in any other kind of infection. Firstly is the urinary tract infections, soft tissue infections and septicemia. Thus if a patient exhibits some of the symptoms such as these mentioned above, it gives a clear indication that the infection or disease must have been caused by a member of the Klebsiella family thus eliminatory measures and attention should be directed to treat the drug resistant bacteria. Careful examination of the patient’s medical history exhibits symptoms recurrence: through histology. As much as the patient has suffered from other forms of infections in the past when associated nosocomial infection occur, then it is a cause to be concerned about the likelihood of the drug resistant bacteria. Largely Klebsiella ozaenae bacteria are known to affect the upper parts of the human body. After careful examination and analysis of the patient, the patients exhibits symptoms of abdominal pain and general pain in the upper torso of the body. As much as she has diabetes Mellitus with no allergy, recurrence of associated symptoms is a confirmatory factor. Growing global resistance to agents is a concern and thus only proved agents that have been confirmed to suspect the bacteria must be used.
Klebsiella ozaenae bacteria have been reported to resist antibiotics and general medications. Thus, to avoid further resistance, which would make the orgasm stronger and difficult to, counter in future, and appropriate medication should be solely based on known chances and cases for susceptibility (Stalker & McBRIDE, 1987, p.959). Therefore, there should not be a trial and error mechanism. The choice of agent should be based on local antimicrobial sensitivities, the actual location of the infection in the human body, economic considerations in terms of the cost factor and comorbid conditions. After comprehensive immunochemistry and serology were conducted, the following are some of the antibiotics recorded to have subdued the bacteria. They include Ceftriaxone 1-2 grams q12-24, Ciprofloxacin 400mg q12 (severe: 400mg q8h), Levofloxacin 750mg IV once a day, Piperacillin-tazobactam (3.375 grams IV q 6h). These are basic agents that showed susceptible strains to the resistant and ever mutating bacteria. Proper and adequate nutrition must then be adhered to by the patient since some of these antibiotics are so strong and might be severe to the human immune system. Extended spectrum beta-lactamase (ESBL) production is a growing problem; nonetheless it has exhibited susceptible strains, and I would recommend Imipenem 500mg IV every 6 hours with arrange of 250-1000 mg q6-8h (Stoor, Söderling & Grenman, 1999, p. 850).
In the above essay, I have highlighted the drug resistant nature of Klebsiella ozaenae bacteria, its basic characteristics and some of the known medication/antibiotics that have subdued its complexity and growth against the human immune system.
Goldstein, E. J., Lewis, R. P., Martin, W. J., & Edelstein, P. H. (1978). Infections caused by Klebsiella ozaenae: a changing disease spectrum. Journal of clinical microbiology, 8(4), 413-418.
Stalker, D. M., & McBRIDE, K. E. (1987). Cloning and expression in Escherichia coli of a Klebsiella ozaenae plasmid-borne gene encoding a nitrilase specific for the herbicide bromoxynil. Journal of bacteriology, 169(3), 955-960.
Stoor, P., Söderling, E., & Grenman, R. (1999). Interactions between the bioactive glass S53P4 and the atrophic rhinitis‐associated microorganism Klebsiella ozaenae. Journal of biomedical materials research, 48(6), 869-874.