Essays on Trophoblast

Drawing from the seminar presentation, I have gathered that the mechanistic target of rapamycin (mTOR) signals various pathway functions and regulates critical functions in the placenta such as mitochondrial respiration and nutrient transport. Placental amino acid transporter activities are significantly decreased in intrauterine growth restriction (IUGR) with recent experimental research evidence suggesting that the changes directly contribute to restricted fetal growth (Jansson, 2016). In this case, placental nutrient sensing is seen to have a pivotal role in the modulation on resource allocation between the mother and fetus thus affecting overall fetal growth, preventing overgrowth of the fetus and ensuring ...

Vitamin D deficiency during pregnancy: Effects, treatment and the outcomes

The aim of this study is to evaluate vitamin D deficiency in pregnant women and its impact on pregnancy course, the best way of management, and the outcome of this management Bone metabolism in humans is associated with a complex steroid hormone system which comprises of vitamin D (Harvey, et al. 2014). Many reports have suggested the potential benefits of vitamin D across therapeutic areas including vascular health, placental function, metabolism, and immune function (McAree, et al. 2013). Data based on biological and clinical findings suggest the key role of vitamin D in women reproductive health. However, there is ...