Lanza, R P, Robert S. Langer, and Joseph Vacanti. Principles of Tissue Engineering. Burlington, MA: Elsevier Academic Press, 2007.
Ever since its introduction into the market, several people have wondered about the mechanism of action of Apligraf. It is known that Apligraf is a bioengineered skin that helps in speeding up the rate of healing of a wound. However, Lanza, Langer, and Vacanti attest in their book, the mechanism through which Apligraf works to accelerate the rate of healing of a wound is still unknown. However, the authors in the book assert that the acceleration is made possible though the introduction of living cells and growth factors together with cytokines into the wound. The in book, the authors, under the subtitle ...