Thesis Proposal: 1st Draft
How Temperature Effects Platelet Function During Hypothermic and Normothermic Cardiopulmonary Bypass
During the process of Cardiopulmonary Bypass (CPB), the physiology of platelet functions subjected to different temperature conditions largely determines whether a patient will experience increased or reduced postoperative bleeding. This research paper showed that platelets levels in normothermic patients are preserved better than in the hypothermic patients.
Meta-analysis test was applied in numerous peer-reviewed journals. Among the articles I reviewed, one hundred patients were randomized into the normothermic perfusion (35 to 37Cº, N=50) and the mild hypothermic CPB group (27-32Cº, N=50). They compared temperature ...