Essays on Estrogens

Disease pathophysiology

Definition of breast cancer Breast cancer is a malignant growth of cells in the breast. This type of cancer arises in the milk-producing glands when cells begin to divide in an uncontrolled way, forming a tumor. The most common neoplasm in breast cancer is the adenocarcinoma of the cells covering the terminal lobular unit (American Cancer Society, 2016; Stephan, 2016).

Prevalence of breast cancer

Breast cancer is the most common invasive cancer to affect women in North America, with more than 200,000 new cases each year, and worldwide, counting up more than 1,200,000. It is the second cause of cancer ...

Introduction

The large production of bisphenol A (BPA) in the world has been documented because of the increased usage of the same in various industries. The most critical industries that have been using this BPA include those manufacturing containers for foods and beverages, cigarette filters, thermal receipts as well as paper currency. With such a huge provision, it is critical that the basis of such developments only emanates from making the right choices over its uses because its production to a total of 2.7 million tons could be disastrous to the body. The main reasoning here is that the chemical ...

INTRODUTION

Catechol-O-methyl transferase (COMT) is an enzyme that plays a significant role in the metabolism of dopamine (DA) and amounts to approximately 60% or more of DA breakdown in the frontal cortex . The gene expressing the COMT enzyme could affect cognition and functioning of the brain via its action on dopaminergic function. A polymorphic variation occurs in the coding area of the COMT gene (a Guanine to Adenine replacement), changing the amino acid from valine (Val) to methionine (Met) at the codon position 158 (Val158Met) and consequently influencing the thermal tolerance and stability of the enzyme. Allelic discrepancies in enzyme ...