Fatigue
Fatigue is a common condition suffered by individuals undergoing chronic illness. The two main factors responsible for fatigue include central and peripheral mechanisms. Central mechanisms largely arise from proximal events such as neuromuscular junction, which is subdivided into supraspinal or spinal. Peripheral fatigue is caused by muscle contraction activities and includes excitation contraction or muscle bioenergetics. The discussion covers some mechanisms involved in fatigue experiences (Gandevia, 1994).
Voluntary muscle activation
This mechanism associated with central fatigue, accounts for about 15% to 20% of the usual and normal fatigue during continuous or sustained fatigue contraction. The voluntary drive of the muscle incurs difference in ...
