Summary: In the article titled, “Abnormal Cortex Plasticity in Juvenile Myoclonic Epilepsy”, the authors investigate the role of defective motor plasticity in the pathogenesis of Juvenile Myoclonic Epilepsy (Strigaro et al.). Prior to this study, JME was linked to motor cortex hyper-excitability and to the abnormal function of thalamic networks. This study, identifies a new mechanism that can cause JME, a common form of generalized epilepsy seen in children. The motor cortex plasticity was studied using an interesting technique called the Paired Associated Stimulation (PAS). The details of this technique are discussed in the methodology section. The role of ...
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This article is about a study that was conducted to check the abnormal short latency synaptic plasticity in the motor cortex of subjects with Becker muscle dystrophy (BMD). Before the research could take place, the author indicates that the assessment of the cortical function especially with patients with BMD has brought about contradicting results. The researchers used the repetitive transcranial magnetic stimulation (rTMS) so as to explore the excitability of the motor cortex. Therefore, the participants of the study were thirteen patients suffering from Becker Muscle dystrophy. Out of the thirteen patients, six of them are stated to have ...
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