The significant loss of blood calcium commonly characterizes the condition of hypocalcemia. In particular, the loss of calcium is common in the extracellular fluid, and it occurs in greater quantities though it is replaceable by the intestine or the bone (Watad et al., 2016). The condition is a consequence of various clinical entities with the signs and symptoms of neuromuscular irritability. The common conditions of the neuromuscular irritability include the paresthesia, laryngospasm, muscle cramps, seizures as well as tetany. The same instability of the neuromuscular structures appears in the elicitation of the Chvostek’s signs and the common Trousseau’ ...
Essays on Excitability
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Summary: In the article titled, “Abnormal Cortex Plasticity in Juvenile Myoclonic Epilepsy”, the authors investigate the role of defective motor plasticity in the pathogenesis of Juvenile Myoclonic Epilepsy (Strigaro et al.). Prior to this study, JME was linked to motor cortex hyper-excitability and to the abnormal function of thalamic networks. This study, identifies a new mechanism that can cause JME, a common form of generalized epilepsy seen in children. The motor cortex plasticity was studied using an interesting technique called the Paired Associated Stimulation (PAS). The details of this technique are discussed in the methodology section. The role of ...
Summary: The study titled: “The Role of Prefrontal Inhibition in Regulating Fascial Expression of Pain.”, examines the role of pre frontal cortex in the control of fascial expression of pain (Karmann et al.). Expression of pain is determined by a certain factor in the environment (like the availability of caregiver) and also on factors that exist within an individual. Expressing pain is a form of communicating once feelings to others. Understanding expressions may help in assessing the pain in a patient (Craig). Presently, assessment of pain in an individual, is done based on the verbalization of pain by the ...
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ORDER AN ESSAYSummary: The interaction between the limbic system and the subcortical dopaminergic system, is important in the experience of reward by the individual. The hypothesis in the present study is that, increased excitability of the medial prefrontal cortex, exerts a suppressive effect on the interaction between subcortical dopaminergic system and the limbic striatum structures (Ferenczi et al.). Lack of a reward seeking behavior is seen in patients with depression and MRI studies in these subjects have identified increased excitability of the medial prefrontal cortex. This finding was suggested as a rationale for the study. The experiments were designed to demonstrate ...
Summary of the article
This article is about a study that was conducted to check the abnormal short latency synaptic plasticity in the motor cortex of subjects with Becker muscle dystrophy (BMD). Before the research could take place, the author indicates that the assessment of the cortical function especially with patients with BMD has brought about contradicting results. The researchers used the repetitive transcranial magnetic stimulation (rTMS) so as to explore the excitability of the motor cortex. Therefore, the participants of the study were thirteen patients suffering from Becker Muscle dystrophy. Out of the thirteen patients, six of them are stated to have ...
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