Chemistry
Trizivir: Ingredients: 3 synthetic nucleoside analogues with inhibitory activity against HIV-1. “A recently approved antiretroviral looks like a nucleoside reverse transcriptase inhibitor (NRTI), but it acts like a protease inhibitor” (Portyansky 1999).
Active Ingredients:
1. abacavir sulfate, 300 mg (aka Ziagen™) 2. lamivudine, 150 mg (aka EIVIR™ or 3TC™) 3. zidovudine, 300 mg (aka RETROVIR™ or azidothymidine, ZDV or AZT because of Azide functional group).
Additives:
1. titanium dioxide 2. hypromellose 3. yellow iron oxide
Coating on Tablets
Is FD&C Blue No. 2, hypromellose, polyethylene glycol, titanium dioxide and yellow iron oxide
Inactive Ingredients: 1. sodium starch glycolate ...
