Hepatitis type B viral infection is a common and serious disease that is caused by the hepatitis B virus (HBV). HBV is a DNA virus with partial double strands and belongs to the Hepadnaviridae family. One-third of the world’s population is believed to have been infected by HBV of which 6% have chronic HBV infection. Depending on the rate of infection and carrier rate, the world is divided into low, medium and high endemicity regions (Franco et al. 75). The HBV resides in the bodily fluids of an infected individual and is transmitted via the same (Aspinall et ...
Essays on Lamivudine
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Chemistry
Trizivir: Ingredients: 3 synthetic nucleoside analogues with inhibitory activity against HIV-1. “A recently approved antiretroviral looks like a nucleoside reverse transcriptase inhibitor (NRTI), but it acts like a protease inhibitor” (Portyansky 1999).
Active Ingredients:
1. abacavir sulfate, 300 mg (aka Ziagen™) 2. lamivudine, 150 mg (aka EIVIR™ or 3TC™) 3. zidovudine, 300 mg (aka RETROVIR™ or azidothymidine, ZDV or AZT because of Azide functional group).
Additives:
1. titanium dioxide 2. hypromellose 3. yellow iron oxide
Coating on Tablets
Is FD&C Blue No. 2, hypromellose, polyethylene glycol, titanium dioxide and yellow iron oxide
Inactive Ingredients: 1. sodium starch glycolate ...
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