Effect heat has on nociceptors
Nociceptors are pain receptors activated by neuropathic or nociceptive stimuli released during pain towards impending or actual tissue injury (Dubin, 2010). Nociceptors frequently are related to the perception of pain are evoked when the pressure and temperature are at a level considered extreme that can cause injuries to tissues and secondly by toxic molecule and inflammatory mediators. In most instances, these injuries concentrate on one section of the skin, blocking the flow of blood. Heat or cold assists in subsecond somatopic withdrawal response the two act as stimuli to depolarize outer terminals resulting in the production of the receptor ...
