Among individuals aged 13 to 17 years, previously non-vaccinated with BCG, and who are in direct contact with TB, is the combination therapy of INH 900mg + Rifapentine 900mg once a week for 3 months as effective when compared to individuals aged 13 to 17 years who are also previously non-vaccinated with BCG and have completed the gold prophylactic standard of INH 300mg daily for 6 months in preventing active tuberculosis?
ARTICLE CITATION:
Sterling TR, Villarino ME, Borisov AS, et al. Three months of rifapentine and isoniazid for latent tuberculosis infection. N Engl J Med. 2011;365(23):2155–2166.
CATEGORY: Infectious Diseases
APPRAISAL TYPE: Therapy ...
