The G- protein coupled receptors (GPCRs) include a group of receptors that still undergoes intense research. Such research occurs at both academic levels and in the pharmaceutical industry. Several advancements occurred recently in the structure of the G- protein coupled receptors. There appeared new crystal structures as well as ground states and active states. Such advancements in the structure of these proteins helped in the further understanding of the receptors especially in the therapeutic fields. It also possesses an immense impact on the GPCR field (Andrew, 2008, pp.6). Several fundamental factors help in the understanding of these receptors. Such ...
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