VAMP7 Modulates Ciliary Biogenesis in Kidney Cells
Epithelial cells elaborate specialized domains with distinguishable compositions of lipid as well as protein, which include the basolateral and apical surfaces together with primary cilia. For proper functioning of the cell, maintenance of these domains; identity is necessary and requires the selective and efficient SNARE-mediated vesicles fusion that contain newly produced and recycling proteins that have the suitable target membrane. There exist many pathways to carry freshly synthesized proteins to the kidney cells’ apical surface, and the post-Golgi SNAREs, or VAMPs that participate in these distinguishable pathways have not been discovered. There has been implication of VAMP7 in delivery ...
