ABSTRACT
Muscular dystrophy disorders are hereditary neuromuscular disorders in which the skeletal muscles deteriorate progressively due to loss of the functional protein dystrophin encoded by the DMD gene. There are many types of muscular dystrophy and they are classified based on the genetic mechanisms involved. Muscular dystrophy symptoms are usually caused by mutations in the link between cytoskeletal and basal lamina proteins since dystrophin is a sarcolemmal membrane protein (Meregalli M, 2013). Loss of ambulation is also an important clinical milestone in the clinical diagnosis of muscular dystrophy. Respiratory muscles, particularly the intercostal and diaphragm muscles are also affected by muscular ...
