Huntington’s disease (HD) is an inheritable and neurodegenerative disease. It is characterized by progressive psychiatric, cognitive, and motor symptoms. It is significant to familiarize with the phenotypes since patients can present with one or more symptoms of the disease. Loss of balance and chorea are the first symptoms recognized by the patients. However, the families always notice personality or cognitive changes before first symptoms. The disease is most common in races from northern Europe. This paper is set to discuss the etiology and risk factors, pathophysiological processes, clinical manifestations, complications, as well as diagnosis of Huntington’s disease.
Etiology and Risk Factors