The function of golli-MBP is less understood than that of the classic MBP. However, golli-MBP is believed to play an important role in various physiological activities such as the regulation of calcium (Ca) homeostasis especially in oligodendrocytes (OLs) and in T-cells ( Paez et al., 2007). The latter authors investigated this particular property of golli-MBP using fluorescent protein clones, cell lines and imaging techniques. It was revealed that when overexpressed in OL cell lines (N19), the golli proteins activate the elaboration of processes and sheets which retract rapidly following a depolarization with high potassium ions (K+). Simultaneously, a substantial augmentation ...
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