____of December, 2014
Tricyclic antidepressants vs Selective Serotonin Reuptake Inhibitors (SSRIs) in treatment of Depression
In recent decades, SSRIs have become the first-choice treatment for depression. The efficacy and acceptability, as well as cost-efficiency of selective serotonin reuptake inhibitors (SSRIs) versus the older tricyclic antidepressants (TCAs) are studied by many researchers. Most of scholars agree that the both classes of antidepressants are almost equally efficient (Marton, 2003.) According to Marton (2003), a small trend towards greater efficacy of TCAs was found when the outcome was measured in terms of depression scales, and towards SSRIs – in terms of global impression scores. But Faravelli and colleagues (2003) argue that in most studied cases, ...
