Myasthenia gravis (MG) is a type of neuromuscular disease that causes certain muscles to fatigue and weaken. The disease is considered to affect voluntarily controlled muscles such as those involved in chewing, facial expression, speaking, eye and eyelid movements and swallowing. The disease occurs in all sexes and age groups. However, it commonly affects women under 40 years and people aged between 50 and 70 years in both sexes, though it is known to affect older people at large (Sieb, 2014). Within the UK, it is estimated that in 100,000 people, there are 15 cases of the disease. ...
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Myasthenia gravis
Myasthenia gravis is an autoimmune disease characterized by the production of antibodies, which are directed against nicotinic acetylcholine postsynaptic receptors located at the neuromuscular junction. This leads to a gradual decrease in the number of acetylcholine receptors at the postsynaptic neuromuscular junction. There are two different variants of myasthenia gravis, which include the ocular myasthenia gravis and the generalized form of myasthenia gravis. The result of the reduction in the number of acetylcholine receptors lead to a concomitant reduction in the muscle strength (Paul, 2000). However, there is recovery of the muscle strength resting it for some time (Kulkantrakon & Jarungkiatkul, 2010), ( ...
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