Pregnancy presents a unique condition and it is of utmost importance by the care provider to conduct all the necessary assessments not only for the purposes of securing the health of the mother but also that of the unborn (London et al., 2015). The first weeks of pregnancy present a unique phase of pregnancy since most birth defects occur during these initial weeks. Examples of the defects include; neural-tube and congenital defects. This makes it necessary to conduct thorough and comprehensive assessment of the unborn and the mother so as to prevent the occurrence of these conditions. As such, ...
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1.0 Background of Immune Tolerance
The immune system is the natural defense that combats disease causing agents in the body[ CITATION Gre02 \l 1033 ] through an intricate and coordinated interactions of many classes of proteins and cells[ CITATION Len00 \l 1033 ].The immune system has a potential to destroy the body cells but in all vertebrates the system is capable of distinguishing “self” from “non-self” molecules. That way the immune system eliminates pathogens and molecules that are a threat to the integrity of the organism without “self-destructing”[ CITATION Len00 \l 1033 ]. The human body has several mechanisms of either suppressing or eliminating autoreactive immune cells. Some ...
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