In their informative poster, University of Dayton’s Biology Department researchers Ankita Sarkar, Janan Bati and Armit Singh seek to explain the complex genetic hierarchy of eye development through experiments which analyze the development of the eye of a Drosophila Fruit eye from birth to adulthood. According to the experiments, significant changes occur in the eye at the beginning of the third instar stage of development. It is at the third instar stage where the fly’s retinal gene differentiation occurs. According to the researchers, “a wave of differentiation sweeps from the posterior to the anterior margin” of the ...
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Summary
The process of developmental of the eye of Drosophila is an important tool for understanding growth and pattern formation of tissues (from poster provided). Cellular interactions and intercellular signaling play a crucial role in this process. In the primary third instar stage an upsurge of differentiation sweeps from the posterior side to the anterior side of the eye disc. The advancing region of this wave is characterized by a morphogenetic furrow (MF), which leads the wave through production of decapentaplegic Dpp and Hh proteins, which subsequently activate the transcription of RD genes. The Dpp serves as a morphogen that ...
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