A review of the article by Jankowska, et al., 2008, titled “Reduction of human chorionic gonadotropin beta subunit expression by modified U1 snRNA caused apoptosis in cervical cancer cells” Jankowska, et al in their article published in the journal “Molecular Cancer” demonstrate the expression of hCG-beta in cervical cancer and examine the functional significance of hCG- in-vitro cervical cancer cells by making use of modified U1snRNA to silence the mRNA of hCG-. Silencing of the maturation of mRNA by use of a novel silencing technique results in inhibition of growth and apoptosis of cervical cancer cells. Lipofectamine 2000 ...
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1) What blood test would you order and why? (1 point) - Quantitative hCG blood test: measures serum beta human chorionic gonadotropin levels (US FDA, 2013) - Above normal hCG values: determines if patient is having a normal pregnancy and the number of fetuses as well as gestational age, or if amenorrhea is due to hydatidiform mole, choriocarcinoma, or ovarian cancer (Ratcliffe et al., 2008; US FDA, 2013) - Below normal hCG values: indicates ectopic pregnancy, fetal death, incomplete abortion, or threatened spontaneous abortion (US FDA, 2013) 2). What is her estimated date of confinement (EDC) ...
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