Problem statement for research purpose: Hypertension can be a cause as well as a consequence of chronic kidney disease (CRD). A number of clinical studies have identified the harmful effects of uncontrolled hypertension on the kidney function (Kokubo, 2012; Berlowitz, 2016)). According to NIH statistics, 23.3% individuals without CKD had hypertension in a representative sample. On the other hand, 35.8% of individuals in stage 1, 48.1% in stage 2, 59.9% of stage 3 and 84.1% in stage 4-5 CKD had hypertension (National Institutes of Health, 2010). In stage 4 CKD, the glomerular filtration is the lowest at <15 ...
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