Diabetes is a chronic metabolic disorder, which is based on the formation of insulin deficiency and an increase in blood glucose levels. Among metabolic disorders the diabetes occupies a second place after obesity. In the world about 10% of the population suffer from diabetes, however, when one considers hidden form of the disease, this figure can be 3-4 times higher. Diabetes develops due to chronic deficiency of insulin and it is accompanied by disorders of carbohydrate, protein and fat metabolism. By interfacing with other diseases endocrinology highlights symptomatic (secondary) and true diabetes. Symptomatic diabetes accompanies diseases of the endocrine ...
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Type 2 diabetes is also referred to as NIDD, which stands for non-insulin dependent diabetes. This diseases presents no symptoms at an early stage but then advances from insulin resistance to hyperglycemia and then full blown diabetes that requires medical attention. The most prescribed course of treatment is the use of sulfonylureas with diet and exercise. Type II diabetes can be attributed to mutations in various genes (Halsted and Edelman, 2000). Risk factors that increase the chance of getting Type II diabetes are aging, being inactive and obesity (Halsted and Edelman, 2000). Glipizide was first commercially marketed in 1984. ...
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