Essays on Amide

Click Chemistry describes the biocompatible reactions that are high yielding, that are very simple to perform, have wide scope, that need no chromatography to remove their byproducts and that can be conducted in easily removable solvents. The synthesis of first triazole was reported by Arthur Michael in 1893. In the 20th century, Huisgen discovered the catalyst of copper, 1,3-dipolar cycloaddition which required the temperature of 100 degree Celsius. This reaction of copper is a highly versatile reaction which does not require any specific reaction conditions and can easily be performed with various solvents, wide temperature range and pH, ...

Surgical Anesthesia

Pharmacology and Indications Licocaine Licocaine is a type of medication used with an aim of numbing tissues and nerves within a given area of the body, which provides that anesthetic effect for the body. The most popular brand names for this particular drug are xylocaine and lignocaine. Some of the common effects associated with this particular medication include drowsiness, muscle twitching, nausea, and confusion (1). The severity of the side effects depends wholly on a patient’s reaction to the chemical composition of the drug. Regarding its mode of action, licocaine works by blocking the voltage-gated Na+ channels, which ...

Abstract

Chymotrypsin is a typical digestive enzyme which is mainly used in the digestion of proteins through a process commonly known as proteolysis. The enzyme chymotrypsin often cleaves bonds of peptide amide preferentially where a carboxyl side of that bond is a tryptophan, phenylalanine or tyrosine.

In this experiment, the chymotrypsin molecules were arranged in such a manner that all the enzyme molecules began the catalytic process at the same time. The rate at which the p-nitrophenol was being generated was initially rapid which was then followed by a much slower hydrolysis rate at steady state.

Therefore, the experiment essentially did sort to establish the concentration ...