Essays on Naloxone

Essay

Chapter 17. Prevention Programs Describe the key characteristics of community based drug prevention strategies. Please list these descriptions in bullet point format Community based drug prevention strategies are very broad (they involve community’s youth, parents, businesses, media, schools, law enforcement, religious or fraternal groups, civic or volunteer groups, healthcare professionals and government agencies with expertise in the field of substance abuse), Community based drug prevention strategies are to be integrated to increase public support, social awareness and to keep the community members informed of the current state of things,

Community based drug prevention strategies are expected to have a structured organizational plan aimed to reach at-risk population,

Community based drug prevention strategies might be oriented to ...

The article underscores the significance of the Centres of Medicare and Medicaid Services (CMS) in the identification and treatment of disorders related to the use of opioids among million Americans. In particular, the article explores the strategies by Medicaid in the prevention of harms resulting from the use of opioid. Over the years, many Americans have become victims of opioid which has led to increased cases of addiction resulting from overdose. Between 1999 and 2011, the number of deaths resulting from the overuse of opioid has increased fourfold (Wachino, 2016). In 2013, 37% of the number of deaths in ...

Suboxone is a combination drug, administered sublingually, of buprenorphine HCL and naloxone HCl dehydrate in a ratio of 4:1, used for the treatment of opioid addiction, for example in heroin addicts and narcotic painkiller abuse, in higher doses; and in lower doses is used for the treatment of acute and chronic pain (FDA, 2010). Buprenorphine is a μ receptor partial agonist and a κ receptor antagonist; naloxone is an opioid receptor antagonist, which has a higher affinity for μ receptors then full agonists do and can thus displace the full agonist from the receptor reversing the effects of opiate overdose, such as respiratory and ...

There are four major classifications of drug actions on the human body. These are stimulants, depressants, hallucinogens, and narcotics. These are the four main classes of drugs used in most parts of the world (Walsh & Schwartz-Bloom, 2007). Stimulants, just as the name suggests, “stimulate” or “increase” body activities and processes. Some are legal and widely used in the world. However, all stimulants are addicting. Heavy use of stimulants has both short term and long term effects. The short term effects include depression, headaches, exhaustion and apathy. The short terms effects include addiction, irritability and feelings of hostility and ...

Reducing Drug Induced Deaths

During the year 2005, approximately 22m Americans were experiencing alcohol or drug related problem. Around 99% of people who abused substances or drugs were not aware of the problem they were experiencing. 273, 000 people out of those who identified their problem unsuccessfully sought treatment of their identified problems. The problems suffered included domestic violence, homicide, suicide and motor vehicle accidents/ crashes. These incidences emphasize the importance of enhancing measures to prevent and treat substance/ drug abuse and their related disorders. Such measures will improve the safety, health and life quality of the victims. This paper explores the 2020 ...

1. Which of the following is an antidote for benzodiazepine overdose or toxicity?a. Buspirone (BuSpar)b. Hydroxyzine (Visteril)c. Flumazenil (Romazicon)d. Naloxone (Narcan)There is one other drug overdose antidote in the above list. Name the drug and its mechanism of action. Flumazenil (Romazicon®) is another drug given to reverse the depressant effects of benzodiazepine and thus useful for overdose treatment. It acts as a competitive antagonist of benzodiazepines, having high affinity to GABAA receptors, which is the BZD binding site. This allows it to specifically target benzodiazepine and drugs with similar MOA such as zolpidem, but not other ...

Vicent’s case study

Question 1- Discuss in point form The clinical features of the scenario that lead you to administer oxygen. The clinical scenario that lead you to administer oxygen; cyanosis, level of consciousness indicated with GSC 7, respiratory rate of 4 breath per minute which is regular but shallow, lowered pulse rate which is weak and regular are the clinical features that are responsible for the initiation of oxygen administration.

The physiological rationale for administering oxygen.

The physiologic rationale is to manage hypoxia and thus reduce the cyanosis, which is the result of shortage of oxygen and increased concentration ...

Section 2. Drug Metabolism

1. i. Referring to the primary literature, investigate the metabolism of paracetamol; Using a diagram as an aid, explain the metabolism of paracetamol noting the types of reaction (functionalisation, conjugation) and enzyme families (CYP, UGT, SULT) involved in these pathways. There are two primary metabolic pathways for paracetamol within the liver – the first and most common is glucuronidation, wherein the paracetamol binds to the glucuronic acid enzyme. Sulfation, which accounts for most of the rest of these occasions, has the paracetamol combining with a sulphate to form a nontoxic conjugate (Hendrickson et al., 2006). (Hendrickson e al., 2006) ii. ...