Targeted therapies that include small molecule inhibitors and monoclonal antibodies have considerably altered the cancer treatment over the past several years. These drugs are currently a part of therapy for several widespread malignancies, including colorectal, breast, pancreatic, and lung cancers, as well as leukemia, multiple myeloma, and lymphoma. The action mechanisms, as well as toxicities of targeted therapies, are different from the action mechanisms of traditional cytotoxic chemotherapy. Targeted therapies are usually better endured than traditional chemotherapy, although they are linked to a number of unfavorable effects, like cardiac dysfunction, acneiform rash, proteinuria, thrombosis, and hypertension. Small molecule inhibitors are acted ...
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