Essays on Biologic

Thesis

Improved Detection and Characterization of Obscured Central Gland Tumors of the Prostate:

requirementsRequirements for the degree of

2016

©2016 by All rights reserved Approved by First Reader Boris Nicolas Bloch, M.D.

Associate Professor of Radiology and

Director of Bioimaging Science Second Reader Kevin Thomas, Ph.D.

Assistant Professor of Bioimaging and Health Emergency

DEDICATION I would like to dedicate this work to my patient spouse Landry, my wonderful children Charlie and Phoenix, and my dog Armani. (Delete this page if you don't need it. Be sure to delete all the text on the page, and the page break after it, not the section break before it. To see the section and page breaks, ...

Chapter I: Introduction

In the United States, Prostate cancer (PCa) is the most common non-cutaneous malignancy after lung cancer in men with an incident of 126 per 100,000 people. The American Cancer Society (ACS) reported that the number of new cases of men diagnosed with PCa by 2016 will be an approximately 180,890 cases. PCa is still considered as the second leading cause of cancer death in men. Also, the ACS added that the estimation for death will occur from PCa is 26,120 deaths in 2016. Today, many studies stated that mortality rate is gradually decreasing compared with the ...

Ahmad, A. (2013). Pathways to Breast Cancer Recurrence. ISRN Oncology, 2013, 1-16. http://dx.doi.org/10.1155/2013/290568 In his article, Ahmed gives an overview of the current knowledge regarding the recurrence of breast cancer after treatment and the challenges. He reviews existing literature on epithelial-mesenchymal transition (EMT), cancer stem cells (CSCs), various signaling pathways such as microRNAs (miRNAs) and Notch/Wnt/Hedgehog. Also, he also examined the hypotheses that are currently undergoing an investigation to determine the prevention of breast cancer recurrence (Ahmad, 2013). Andre, F. & Zielinski, C. (2012). Optimal strategies for the treatment of metastatic triple-negative breast cancer with currently approved agents. Annals of ...

Pediatric Case Study

Part I. Cultural and Family Assessment

Culture and family are oftentimes neglected during patient assessment, especially when the person is viewed only in terms of disease, causes and treatment. However, providing holistic care that encompasses all aspects of the patient’s life has the potential to improve patient outcomes. In nursing theory, Callista Roy and Madeleine Leininger refer to culture as a belief system, a worldview through which the patient perceives health, care, nursing and the world in general (George, 2011). It is transmitted from one generation to the next through interaction in social institutions such as the family, school and ...