Pharmacogenomics alternatively referred to as pharmacogenetics in medical literature is a component of personalized medicine. It refers to the study of genetic polymorphisms that in one way or another influence individual response to drugs. Clinical observations on the effects of genetic polymorphism on the pharmacokinetics and pharmacodynamics of drugs were first documented back in the 1950s. Scientific knowledge on genetic variations is therefore the critical foundation on which pharamacogenomics is based. In specific, the knowledge of how variations in the genes responsible for encoding enzymes and proteins are the main pillars of pharamacogenetics (Belle, 2008). Enzymes play a vital role in ...
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1. The chemical name of salbutamol is α1-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α,α’-diol; α1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol;CAS Reg. No. 18559-94-9. The molecular formula of Salbutamol is C13H21NO3. It is a white or almost white, crystalline powder and is odorless (World Health Organization 2006, p.845). It belongs to the category of antiasthamatic drug. The generic name is Salbutamol (Elling, Jackson & Jackson 2007, p. 121). The Australian trade name of Salbutamol is Albuterol (AMH, 2011). 2. a. Salbutamol is specifically indicated in the following conditions:
Asthma(acute)
Reversible obstruction of airways (Including COPD) and other similar conditions and maintenance asthma ...
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