Genetically acquired disorders and characteristics can easily be transferred from the parents to offspring. Genetic counselling is an endeavor to educate the parents and make them aware of the impacts of their genetic composition on their future offspring. Diseases such as erythroblastosis fetalis result from the incompatibility between the father’s genetic composition and the mother’s, resulting in to a fetus with hemolytic anemia. It is therefore imperative that the parents are counselled on the various genetic characteristics which can result into problems on their born children. Genetic counselling is the process by which a parent is counselled ...
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1.0 Introduction Serological blood grouping has been used successfully for decades to ensure safety in blood transfusion. However blood incompatibility continues to be a significant challenge in transfusion medicine reflecting the inherent limitations of the hemagglutination based serological blood typing. Some of the limitations of serological blood grouping include weak reactivity of some antibodies that are clinically significant; weak expression of some red cell antigens; the subjective nature of the available tests and lack of universal methods of detecting and identifying antibodies. In addition there are several issues related to the reagents used which include the wide variability of ...
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