Essays on Cd8

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Immunotherapy in Treating Human Cancer

The immune system of our body is a complex network of tissues, cells, and organs that act mutually to protect our body from unknown foreign trespassers. It recognizes the harmful particles entering the body and facilitates the destruction of those particles in order to shield the body system from any ailment. Due to any complexity or disturbance often the immune system targets the wrong particle considering it as a dangerous particle and this anomaly of the immune system may result in various autoimmune diseases like arthritis, allergies, malignancies, and AIDS (Understanding the ...

Immunology

The rearrangement of T cell receptor (TCR) genes g and d occur in series of cells expressing variable Vg and Vd gene segments. The lymphoid precursor cells originate in the bone marrow and move to the thymus. Preliminary T cells are devoid of TCR, CD4 and CD8 molecules and are called double negative thymocytes . These double negative T cells may be further categorized into four phases of differentiation (DN1, CD44+CD25-; DN2, CD44+CD25+; DN3, CD44-CD25+; and DN4, CD44-CD25-) . CD44 is a cell adhesion molecule and CD25 serves as the IL-2 receptor. Passage into the DN2 and DN4 stages ...

Cell Mediated Immunity

Cell mediated is one of the components of the immune response. it involves the expression of cells like natural killer cells, phagocytic cells and antigen-presenting cells. it also involves the release of various forms of cytokines. the varies ways by which cell mediated immunity protect the body includes the activation of macrophages and natural killer cells in order to empower them to destroy antigenic agents like pathogens. it also leads to the formation of substances that modulate the function of cells involved in cell-mediated immunity. In addition, cell-mediated immunity helps in protection of the body by leading to activation ...