Essays on Guanosine

Abstract

The literature defines hypertension as a medical condition experienced when the systolic blood pressure (BP) is equal or greater than 140 mm Hg or when the diastolic blood pressure is equal or greater than 90 mm Hg. Additionally, it offers a description of systematic, cellular, as well as molecular causes of hypertension. High blood pressure within the arteries is referred to as systemic hypertension (SH). The primary role of the systemic arteries is the transportation of oxygenated blood from the heart to the tissues of the body. The constriction of the arterioles (small arteries) is responsible for the high ...

Eukaryotic organisms’ cells are composed of different types of primary and processed RNAs. These RNAs are locally found in the nucleus, cytosol or throughout the cells. To understand the function of RNA as a type of protein, RNA profiling has been carried out leading to the birth of a genomic project known as “ENCODE or the Encyclopedia of DNA Elements”. The goal of the project is to identify and characterize functional elements that are present in the genes (Djebali et al.). In the paper Landscape of Transcription in Human Cells the study tries to answer the general question: should the ...

- Abstract Cardiovascular diseases such as heart failure are some of the leading causes of mortality and morbidity with Australia being one of the country’s most greatly affected (McLean, Esclick & Coats, 2006). An area of interest in the pathology of heart failure is the significance that polymorphisms of adrenergic receptor genes have on the outcomes of patients with heart failure. Single-nucleotide polymorphisms or SNPs that occur in the genes that encode for adrenergic receptors are known to have various physiological and functional consequences. Specifically, the β1-adrenergic receptors have a crucial role in the regulation of heart rate and ...