Essays on Localizing

1.0 Introduction KFC, the world’s largest fried chicken chain restaurants, was started in 1952 by Harland Sanders, under the name Kentucky Fried Chicken though the idea was first discovered in 1930 when Sanders started to sell fried chicken to visitors in Corbin Kentucky. It is the second largest restaurant chain, with about 1800 locations, with over 3000 stores in China, and a revenue of about $ 15 billion, McDonald’s is the first (Hu & Xie, 2013). In 1939, Sanders came up with an original recipe for fried chicken incorporating 11 spices that are kept at the Company's headquarters in ...

Gun control has always been a conscientious and hotly debated topic in the United States of America. Either side of the debate are the gun control and the firearm rights activists, each giving their own interpretation of the law and asking the government to intervene in the matter. The right to bear arms is a constitutionally granted freedom to the citizens of the country and can be found in the second amendment to the constitution. The government is also responsible for the safety of the citizens and prevent them against crime. The cause for the debate stems from the ...

Abstract

A-kinase anchoring proteins (AKAPs) are a group of structurally varied scaffold proteins which are found to regulate the PKA pathway by localizing the protein kinase A and some specific enzymes at sub cellular level. So far several of the AKAPs have been found to play critical role in the regulation of phosphorylation of several PKA dependent substrates which are necessary for the modulating the cardiac function. Abnormalities in these AKAPs genes have been found to cause various forms of cardiac disease. The most prominent AKAPs are the AKAP9 and AKAP13. Mutations in the AKAP9 gene has been found to be ...