Cancer antigen 125 (CA125), which is encoded by MUC16, is the only biomarker currently used for immunohistochemical diagnosis of ovarian cancer (Tanyi and Scholler 1098). Literature suggests that 80% of the patients with ovarian cancer express CA125. The expression pattern is different among the different kinds of ovarian cancer; 85% in serous ovarian cancer, 12% in mucinous cancer and 40% in clear cell carcinoma (Tanyi and Scholler 1098; Kaspar and Crum 44), which helps in differential diagnosis.
Differential diagnosis among various types of ovarian cancer. There are five types of primary ovarian ...
