Propylthiouracil Essay Examples - Only The Best to Spark Your Inspiration!

Rat Endocrinology

Hypothalamus 1. What is the molecular mechanism to release TRH? TRH refers to the thyrotropin-releasing hormone. This hormone is produced by the hypothalamus. Before the full activity of TRH, some tightly controlled processes occur in the body including the appropriate folding of prohormone to move to the secretary pathway, the processing after translation, and movement of the peptides, which are processed, towards the secretary granules for secretion (Nillni n.p.). TRH develops from bigger inactive precursor (known as proTRH) as a result of modifications after translation and moved through the controlled secretary pathway. Prohormone convertases (abbreviated as PCs) including PC1/3 ...

- How would propylthiouracil affect metabolic rate in a normal rat? Explain why.

It would decrease metabolic rate since propylthiouracil decreases the production of thyroid hormone (“Propylthiouracil,” n.d.).

- Explain the action of insulin on body cells.

Insulin acts on the body cells by promoting absorption of glucose from the blood stream to the body cells. This is done when insulin attaches to the insulin receptors in cells triggering a response that increases the levels glucose transporters (GLUT4) (Cartailler, n.d.).

- If the body is not producing enough insulin what happens to levels of that substance (your answer to ...