Essays on Protein C

The case of James a 48 year old male is a case of a patient with DVT but with little information. This man is a lawn tennis player with some issues that made him visit the emergency room and had the boot placed on him for 4 weeks duration. It was after that episode of medical management that he noticed a form of ankle to calf swelling on one of the legs. The swelling was really abnormal in terms of size hence he needs to see the doctor urgently. Despite swelling and the test such as ultrasound done, the extent of severity to him ...

Abstract

Factor V Leiden is a genetic mutation that confers resistance to the action of activated protein C and thus predisposes to venous thromboembolism. It’s inherited as an autosomal dominant trait and is prevalent amongst Caucasians with a carrier rate of 4%. Deep venous thrombosis and pulmonary embolism are the most common clinical manifestations of FVL related VTE although it can also affect other sites. Genetic testing for FVL is used for diagnostic as well as predictive purposes. Diagnosis of FVL is based on protein assays and

DNA analysis technology. Familial genetic testing for FVL is generally not recommended except in ...

Introduction

The term “risk factor” is very common in epidemiology. In general sense, it refers to a particular variable that is associated with an elevated risk of infection or disease. Since the number of diseases in the world is very large, the number of risk factors is also every large. The risk factors however vary from one disease or infection to another. However, there are a number of risk factors that are very common and play a significant role in many infections. One of these factors is molecular genetics. As the name suggest, molecular genetics is a genre that mainly deals with the functions ...