"Are Protein-Protein interactions likely to be valid therapeutic targets for cancer therapy?"
In her paper entitled “Protein-Protein interactions and cancer: small molecules going in for the kill” Michelle Arkin raises questions regarding the grooved and linear regions that permit protein-protein bonds, the binding peptides also found in those regions, if those interfaces are tractable for small molecule discovery and what compounds might serve as bonding agents. Further investigation of compounds would include if they are active, inhibiting, and do they help further characterize the target. She documents tubulin and several others that have potential. Her conclusion confirms that ...
Replication Literature Reviews Samples For Students
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Abstract
This paper seeks to explain the views by the various literatures about the value of information. Information as seen exhibits some characteristics which include expandable, compressible, substitutable, transportable and diffusible and as such this paper will explain the characteristics of information. Information in the economy is considered a distinctive good and its unique features can be seen in the basic consideration of costs. The paper will explain the explain information as an economic good and the paradoxes that are brought about by the analysis of the economy. Also information services are regarded as a public good as most of its qualities ...
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Introduction of restriction enzymes
Restriction enzymes are highly diverse set of enzymes in bacteria that are used to identify specific 4- to 8-bp sequences referred to as restriction sites and cleave DNA strands internally at this site. These enzymes protect the bacteria from foreign DNA molecules such as those of phages. Restriction enzymes identify specific nucleotide sequences to differentiate between the “domestic” and “foreign” DNA. It attaches to the “recognition site” and breaks both strands of the DNA (Kufe et al.). Restriction enzymes may include EcoRV, EcoRI, and HindIII. EcoRV belongs to the type II restriction/modification system ...
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