Thalassemia College Essays Samples For Students

Epidemiology of Thalassemia among the population of Malta

This discussion is about epidemiology of thalassemia in Malta. Thalassemia is the given name of a category of genetic blood confusions typify by anemia because of augmentation of red blood cell destruction (Barnes, Plotnikoff, Fox, and Pendleton, 2000). Hemoglobin, it is the conducting of oxygen of the red blood cells dwelling by the two diverse proteins which are the alpha and beta. In case that the body doesn’t construct sufficient with these two proteins, the red blood cells is inadequate and cannot bring enough oxygen (Sembulingum K. Et Al, N.D.). It is a severe with a more than few of health ...

Beta thalassemia is an inherited blood disorder triggered by the absence or reduced production of hemoglobin. It is regarded as a genetic or hereditary insufficiency in the permutation of beta globin chains (Galanello and Origa). A newly born child needs two globin genes from each of the parents to generate beta globin chains. If one or two of these genetic factors or materials are deficient, it will form into the beta thalassemia disease. Moreover, beta thalassemia also hinges on how many genes are transmuted. Beta thalassemia minor is produced if only one of the globin genes is mutated. If both ...

Orphan Drug

Introduction
The main purpose for the enactment of the U.S. Orphan Drug Act (ODA) of 1983 is to conduct a research on some of the rare diseases whose medical needs remain to be unresolved.
The law has given incentives to various sponsors who have tried to develop therapies for some of the rare medical conditions that can affect at least 200,000 individuals on a yearly basis (Premiere Research 1). For this study, the objective is to create a regulatory strategy or path for Orphan Drug development, particularly on the oral iron chelator, one of the subsets of thalassemia or ...

In clinical transplantation, an observed complication is that previous red blood cell (RBC) transfusions may reduce the risk of solid organ transplant rejection but increase the risk of bone marrow transplant (BMT) graft failure (Storb and Weiden, 1981). This statement is seemingly a contradiction. It is difficult to understand how RBC transfusions can both reduce the risk of solid organ transplant rejection and increase the risk of BMT rejection.
But this contradiction can be resolved by understanding three considerations. First, the immune system is extremely complex and attempts to control its effects routinely have both positive and negative effects ( ...

Child and adolescent health issues require extra concentration due to the fact that an early disease can lead to an improper growth which may impact the entire life of a person and therefore it is important to ensure that childhood and adolescence diseases are looked after with extreme care in order to improve the quality of life and the growth of the patients. Sickle cell anemia is one of the widely studied subjects today, considering that it can cause acute chronic conditions which include severe pain and organ dysfunctional ties and has a high fatality rate. This disease is also known ...