Essays on Hemoglobin

Sickle cell disease is a genetic blood disorder that affects the hemoglobin, the protein molecule in the red blood cells responsible for delivering oxygen to the body cells and throughout the body. The disease is characterized by the presence of abnormal hemoglobin that forces the red cells to assume a sickle shape. Normal blood cells are disc-shaped which allows them to be flexible as they navigate through the blood vessels. The abnormal hemoglobin forms rod-like structures immediately after unloading the oxygen. The sickle-shaped red blood cells are inflexible making it difficult to navigate the blood vessels and can stick ...

Anemia

This is a condition that normally develops when blood lacks enough hemoglobin or red blood cells. Hemoglobin being part of the red blood cells is responsible for binding oxygen. When one has abnormal or too few red blood cells or the hemoglobin is low or abnormal, the cells in the body will lack enough oxygen (World Health Organization. 2015). Symptoms like fatigue occur in people with anemia because the body organs lack what they need to operate appropriately. Other possible symptoms are; feeling tired, a feeling of the heart racing, feel having short of breath, experiencing worse heart problems ...

In Diabetic type II Patients, how does Self-Management Education Affect Overall Health Care Cost?

Introduction Self-management education is a fundamental paradigm that helps a majority of diabetic patients from severe consequences associated with the disease. Since debates type 2 is one of the chronic diabetic conditions, proper DSME is an appealing solution that provides a firm foundation to diabetic patients towards an overall improvement of their health conditions and physical activities (Kumar, & Snooks, 2011). In addition, DSME has been shown to be an intervention that improves on the overall health outcome of these patients. DSME often involves processes that facilitates the knowledge, skills, and the ability that aid with the prerequisite techniques for ...

Response 1

Upon the loss of blood, the patient’s body will be stimulated through the action of erythropoietin produced by the kidneys to increase erythropoiesis. The result is the increase in the concentration of reticulocytes that will be seen in the peripheral blood smear. The reticulocyte will peak to range between 10 to 15% by the seventh day after the blood loss.

Response 2

The hypoxia is as a result of inadequate delivery of oxygen into the tissues. Hemoglobin is responsible for the transport of oxygen into the tissues. Hypovolemia causes a significant reduction in the level of hemoglobin which results in ...

Diabetes is a burning issue all over the world. World health organization has shown concerns on the prevalence and incidents of diabetes. In USA, 29.1 million people or 9.3% of the population; diagnosed or undiagnosed have diabetes. (CDC, 2012). As per National Diabetes Fact Sheet, 2011 215, 000 people in USA have type-I or type-II diabetes. Thus, diabetes is a disease penetrating all age groups. Treatment of diabetes has a few advancement in the recent past. Apart from general oral hypoglycemic agents and injectable insulin there are islet transplantation surgeries also available for diabetes. There is a wide scope of treatment of diabetes ...

The history of pathology testing is dated back to the 3rd century BC, when Greek scholars such as Herophilos and Eriasistratus began systematically examining dead bodies. At the beginning of the first century AD, several Greek, Roman and Arabian physicists made significant developments in the understanding of the pathology of tumors. In the 18th century, Giovanni Morgangi correlated the symptoms of his patients with the pathological evaluations o the autopsies. The discovery of the circulation of blood by William Harvey and the emergence of microsby is regarded as the foundation of modern pathology. The 19th and 20th centuries experienced ...

Background

Pernicious Anemia (PA) is a chronic illness that is caused by impaired absorption of vitamin B-12 due to lack of (IF) intrinsic factor in gastric secretions. It is a condition in which the body lacks a sufficient number of red blood cells (hemoglobin). Present within red blood cells, hemoglobin is important for carrying oxygen in all body tissues. Pernicious anemia is therefore a decrease in red blood cells which occurs when one’s intestines cannot absorb vitamin B12 properly. The body needs vitamin B12 to make red blood cells. Pernicious anemia is most prevalent in Caucasian people of northern European lineage than in ...

The paper with the title “Hemoglobin: A Gas-Transport Molecule That Is Hormonally Regulated in the Ovarian Follicle in Mice and Humans” has been researched and written by researchers from University of Adelaide, Australia. Some of the important points related to this paper have been presented under the questions.

Introduction and Background:

Hypothesis of the paper

Researchers hypothesized and explored the temporal variations of hemoglobin expression and the genes controlling heme biosynthesis. They have also hypothesized that the possible function of hemoglobin is oxygen transport during in vitro maturation under low oxygen incubation conditions and tested it.

Why authors worked on this experiment?

Initially researchers found Hbb and ...

Question a

Diabetes mellitus (also type 2 diabetes) is a medical condition affecting the body’s use and conversion of energy. It may arise from various biological malfunctions such as over-secretion of glucagon hormone, insufficient secretion of insulin and resistance to regulation of glucose levels by insulin hormone. The condition may arise either from poor diets or from the effect of hereditary and environmental factors. Excessive consumption of high calorific foods, minimal exercising and obesity are some of the predisposing factors that may make one susceptible to the disease. This is especially so when these factors supplement genetic factors. The main risk ...

1. What is Normal hematocrit ranges?

The normal hematocrit ranges are dependent on two things which are the age and sex of the individual. However, it is only dependent on sex after adolescence. The normal hematocrit ranges are: 55%- 68% for Newborn babies, 47% - 65% for one week old babies, 37% - 49% for one month old babies, 30% - 36% for three month olds, 29% -41% for one year olds, 36% - 40% for 10 year olds, 42% - 54% for adult males, and 38% - 40% for adult women.

2. What is Occult blood?

An occult blood is defined as a negligible amount of blood present ...

- Erythrocytes or red blood cells are the most well-known components of the whole blood. They contain hemoglobin, a complex protein, which contains iron. This helps red blood cells to carry oxygen through the body. And this is the main function of erythrocytes. When hemoglobin concentrations fall down and there is no sufficient amount of red blood cells to carry oxygen it is termed anemia. Iron is very important component of the erythrocytes because iron can bind oxygen and transport it to the tissues.

- The blood runs a certain path through the body. It moves through pulmonary circuit and then ...

Introduction

This paper focuses on various tests to determine whether there is need for Red Cross to sort/classify the blood into the various blood types; type A, type O, AB, or B. The aim is to allow the Red Cross to know the supply of each blood type available at any time to help people in need. Another advantage of sorting the blood into various types is that blood can then be stored in a safe place under the right conditions to prevent the blood from spoiling. The paper begins with analysis of the Business Research Methods that emphasizes on testing ...

Keywords : Gene therapy, Sickle Cell Anemia, Stem cells, lentivirus, β-globin

Project type: GBE-492 Genetic Engineering Project I. INTRODUCTION, BACKGROUND and AIM Sickle cell anemia is a devastating genetic disease which causes premature death. Sickle cell disease (SCD) is caused due to single amino acid change (glutamine to valine at position 6) in β chain of hemoglobin molecule, which causes the hemoglobin molecules to aggregate. These aggregated hemoglobin molecules make the red blood cells (RBCs) stiff and deformed (sickle shaped). These deformed cells block the normal blood flow. Although this disease is well-characterized, but no long-term treatment 1 is still available for this disease. The discovery of the sickle ...

Glycosylated Hemoglobin: HgA1c

Glycosylated hemoglobin is formed by the irreversible, non-enzymatic binding of circulating glucose to the amino groups of lysine and valine residues in hemoglobin. It is measured as a ratio of glycosylated hemoglobin to non-glycosylated hemoglobin. The level of HgA1c in erythrocytes depends on the concentration of glucose in blood. When level of blood glucose is high, the rate of glycation is increased, hence more glycosylated hemoglobin. Glycation occurs slowly and over the entire lifespan of the red blood cell, i.e. 90-120 days. Therefore, HbA1c reflects the average level of blood glucose exposed to the red blood cell over the past ...

Abstract

Proteins are made up of amino acids and have major structural as well as functional roles in the body. Amino acid chains are synthesized from DNA sequences through transcription and translation. Proteins become fully functional only after co-translational or post-translational modification of the amino acid side chains and folding into appropriate three-dimensional conformations. Even slight changes in the DNA code could drastically alter the protein folding, alter its functioning, and eventually lead to certain diseases. Inherent cellular repair mechanisms, protein degradation pathways and molecular facilitators such as chaperones try to keep proteins in their native, stable conformation by acting ...

T.A. is at increased risk of infections due to several factors. To start with, He admits smoking one pack of cigarettes per day. As a result, he is at risk of developing lung cancer and cancer of the mouth, throat, lips, kidney, stomach, and other organs. Furthermore, smoking leads to increased risk of the following conditions: heart attack, cerebrovascular disease, coronary heart disease, peripheral vascular disease, emphysema, chronic bronchitis. These conditions are likely to weaken his immune system. As a result, his is prone to infections. T.A.’s laboratory results also show hemoglobin A1C level of 7.9% and serum glucose level ...

Abstract

Sickle Cell can be a very frightening disease, not just because the disease itself is deadly but because of the stress it puts on one’s body. Being a mom who suffers with Sickle Cell Trait and has a child who suffers with the disease opens my mind to a lot of questions. Though I suffer with the disease my symptoms are mild to none, but however my son who suffers worse, has the bad end of the deal, because not only does his body goes through painful crisis, but just about anything can trigger off his pain. Thankfully there are different types ...

The binding of antibodies to red blood cells can lead to potentially fatal outcomes such as hemolytic transfusion reactions, autoimmune hemolytic anemia, and hemolytic disease of the fetus/newborn.1 Information regarding the first steps of hemolytic transfusion reactions is well documented. It is, however, unclear why the severity of hemolytic transfusions experienced by different individuals ranges from mild to very severe.2 The pathophysiology of the final pathways and downstream events of red blood cell hemolysis are also yet to be fully elucidated although research is ongoing.2 A recent study by Liepkalns et al. (2012)1 has reinvigorated debate on the ...

Introduction

Blood consists of erythrocytes and leucocytes suspended in it. Blood is pumped from the heart to the body through the arteries and it enters back in the heart through the veins. Blood without cells is known as plasma while serum is the straw colored liquid obtained after the removal of the clot. Plasma contains different proteins, nutrients and waste materials. There are different cases of blood disorders observed in humans.

Blood cells and platelets

The most abundant cells in the blood are the anucleate, biconcave erythrocytes. They contain a red pigment known as hemoglobin (Hb) that carries dioxygen (O2). Hb contains four subunits each ...

Debra Dutton

BIO 201 Pollution and the Human Body The human body has an incredible defense and healing system. It uses the various senses like smell, sight and taste to filter the food, air and water as they get into the body. The skin safeguards the body tissues and internal organs from environmental hazards. The skin also senses the variations in environmental temperatures and acts as the body’s stimuli in controlling the body temperature. The brain and the nervous system are part of the complex response and flight mechanism that responds to emergencies and dangers. An army of ...

Introduction

It will be documented that the oxygen molecule, which basically glides through the air, happens to breathed in via the nose and mouth in the course of inhalation. It then moves from the nose and mouth into the pharynx, precisely, to the nasopharynx and oropharynx. Studies hae extended to reveal that the epiglottis in return closes so as to inhibit foreign substances from flowing into the windpipe (trachea). As it moves from pharynx, oxygen molecule passes through the voice box (larynx) via the trachea. It will be realized that the trachea actually separates into bronchi, which are mainstream branches ...

2. How does exercise affect diabetes mellitus? During exercise, the whole-body oxygen consumption usually increases 20-fold. However, greater increases have been reported in the working muscles (American Diabetes Association). Under such circumstances, the skeletal muscles increase the utilization of stored triglycerides and glycogen, as well as the free fatty acids. Consequently, exercise maintains appropriate glucose levels in order to preserve the function of the central nervous system. In patients with diabetes mellitus, therefore, exercise ameliorates insulin sensitivity and helps to lower the elevated levels of blood glucose to the normal range (American Diabetes Association). 3. How does ...

Importance of Pathology Laboratories to Health Care Professionals in Diagnosis and Treatment of Patients

The history of pathological testing is dated back to 3rd century BC, when Greek scholars such as Herophilos and Eriasistratus, began systematically examining dead bodies (1). Beginning first century AD, several Greek, Roman and Arabian physicists made significant developments in the understanding of the pathology of tumors. In the eighteenth century, Giovanni Morgagni correlated the symptoms of his patients with the pathological evaluations on the autopsies (1). The discovery of the circulation of blood by William Harvey and the emergence of microscopy is regarded as the foundation of modern pathology (2). The nineteenth and twentieth century experienced an accelerated ...

Overview

This case involves the assessment of the client’s problems. The case presents the client’s situations that are relevant to the assessment. In this case, the client’s profile, case study, and pertinent case study questions will be outlined. The following medical terminologies will be employed: alpha-glucosidase inhibitor, Amylin, hyperlipidemia, congestive heart failure, coronary artery disease, hemoglobin A1C level, post-prandial, BMI, diabetic nephropathy, diabetic neuropathy, and diabetic retinopathy. The data obtained from the assessment will help design a care plan for the client.

Ethnicity: Pacific Islander Lifestyle: Sedentary lifestyle and smoking Language: English/Austronesian language Any existing disabilities: None ...

Introduction 3

Definition and background 3 Structure and properties of Artemisinin 4 Structure 4 Properties of Artemisinin 5 Synthesis of artemisinin 5 Activation of artemisinin 7 Mechanism of Artemisinin action in the body 8 Side effect 10 Conclusion 10

References 13

- Table of Figures Figure 1: Structure of Artemisinin2 4 Figure 2: A synthetic strategy of chemical synthesis from cyclohexenone. 7,9,10 6 Figure 3: Reductive scission model: Homolytic mechanisms of bioactivation of the endoperoxide bridge of artemisinin and derivatives 8 Figure 4: Proposed mechanism for artemisinin mediated lipid ...

Objective 2

Introduction 2 General background 3 Resistance mutants 4 Hemoglobin mutants 4 Sickle Cell Anemia and Genetics: Background Information 5 Connection of Sickle cell with Malaria 6 Method: 7 Introduction of Recombinant DNA technology in diagnosing disease: 8 Discussion (implementation of recombinant DNA technology to solve the issue) 9 Conclusions 10

References 11

Objective This report targets to study a group of people that has developed resistance to malaria. It will focus on the use of recombinant DNA technology to study this cohort and gain insights into the nature of this observation. This ...

The pressure of atmospheric oxygen decreases gradually as barometric pressure drops with increasing altitude. The ability to perform work, such as walking and climbing belittles with the decreased availability of oxygen in the atmosphere for aerobic respiration. The Mount Everest is the highest peak on the earth with an altitude of 8848 meters. At such a higher altitude, the partial pressure of inspired oxygen or PIO2 reaches the limit at which humans can maintain body functions, such as cognition and ambulation. In 1953, Hillary and Tenzing used supplemental oxygen while climbing the Everest. It was only 25 years later that ...

1. What are the components of physical examination? Describe each component. The components of the average physical examination include vital signs check, health history updates, physical examinations and laboratory tests. In certain cases additional tests such as MRI (Magnetic Resonance Imaging) and CT (Computerized Tomography) scans are also performed. Doctors use physical tests to check how well the body is performing. Vital sign checks include heart rate, temperature, blood pressure readings and respiratory rate measurements. Updated health history includes a review of current medication, supplements, pre-diagnosed conditions and any new developments including job and relationship status. Physical examinations includes ...

The brain transmits the signal of oxygen requirement and the diaphragm expands that inhales the air. The inhaled air is composed of several different molecules and oxygen is one of the vitals. The respiratory system is a pathway that begins from external organ, nose, from where the air is inhaled. Air passes to the nasal cavity which is lined by ciliary cells that clean, warm and humidifies the air preparing it for gas exchange in lungs. The air then travels through the pharynx that is divided into three regions namely nasopharynx, oropharynx and hypopharynx that are connected with the ...

There are three significant formed blood elements namely- the red blood cells, white blood cells and the platelets. Each elements play important roles in the blood functioning. The most common type of blood cell is the Red Blood Cells (RBC) is primarily responsible for the circulation of oxygen within the human system. They receive oxygen from the lungs then release it into the body tissues. Amongst the blood elements the most predominant cell is the red blood cell. These blood cells contain hemoglobin; they contain iron-containing protein. These iron-containing proteins help in performing the primary function of the blood ...

Sickle cell is a hereditary disease that that has no cure. The disease cause blood disorders and is the most common form of sickle cell disease. The disease affects the hemoglobin in the red blood cell since the disease cause mutation of hemoglobin (Genetics Home Reference 2012). Thus, an individual with the disease produce both normal and abnormal hemoglobin. The sickly abnormal cells block the blood flow. Hence, as the result of blocked blood flow in the body that the cause inflexibility of red blood cells can raise the risk for infection that are life threatening chronic diseases that can ...

Introduction

In previous decades, epidemics were associated entirely with communicable diseases. However, a recent global phenomenon is the significant rise in incidence of chronic diseases linked to individual lifestyles. Unhealthy diet, inadequate physical activity, smoking, and alcohol intake all play a role in initiating the physiologic changes that lead to the development and progression of lifestyle-related conditions including cardiovascular disease, type 2 diabetes, and cancer (Strychar, Elisha & Schmitz, 2012). These are the top causes of death in populations as reported by many countries. Because of the association with lifestyle factors, such illnesses are largely preventable but require complex management once acquired. ...

Question 1 (Word Count = 332) Is there a difference in hemoglobin concentration at enrolment between women with detectable peripheral malaria parasites and those without detectable parasites? In order to test whether hemoglobin concentration recorded at enrolment is different in women with detectable peripheral malaria parasite from those without detectable parasites, a Student t-test is required. Using the student, the mean of two samples are compared to determine whether there is any significant difference between the two samples. Analysis of the data for “Hb at enrolment visit” variable and the “Malaria at enrolment” variable was done using SPSS to ...

Biology for Nursing Practice

(Location of the University)

INTRODUCTION

The earliest recorded use of performance-enhancing substances dates back to the era of the Olympians in Greece, specifically 776 BC (Bowers 1998). ‘Doping’—an overused term in the field of sports—originates from the Dutch word “doop”, a viscous opium juice which was once a favorite of the ancient Greeks. Nonetheless, it is a common knowledge of today that the use of performance-enhancing drugs is banned because of the unfair advantage it gives to sportsmen. Cunning as it may seem, athletes in the 1990s have found ways to improve their performance sans the use of mainstream drugs ...

Nursing

Shea, S., Kothari, D., Teresi, J. A., Kong, J., Eimicke, J. P., Lantigua, R. A., . . . Weinstock, R. (2013). Social impact analysis of the effects of a Telemedicine intervention to improve diabetes outcomes in an ethically diverse medically under served population: Findings from the IDEATel study. American Journal of Public Health, 103(10), 1888-1894. doi:10.2105/AJPH.2012.300909

About the Article

Empirical and theoretical studies suggests that the adoption of innovations indicative of a general pattern revealing that adoption process of the health-related innovations vary according to socio-economic status of individuals. This is one of fundamental principles behind the study conducted by Shea et al. (2013) on the ...

Hemoglobinopathies: Analytic Diagnostic Techniques

Hemoglobinopathies and Thalassemia’s are a kind of Genetic disorders caused mainly by a mutation or deletion of Globin genes in Hemoglobin. Hemoglobin consist of α or β Amino acid chains. An alteration in α chain production leads to α Thalassemia and alteration in β chain causes β Thalassemia. Hemoglobinopathies on the other hand may be caused due to the structural abnormalities or alteration of amino acid sequences in the Globin genes. These are mainly hereditary and constitute to around 4 to 5% of the world population. (WHO Statistics, 2012) Each year around 250,000 to 300,000 new born children have either hemoglobinopathies or thalassemia. Both ...

This paper will talk about pregnancy. It will give the physical and the psychological changes that the pregnant mother will experience throughout the period of pregnancy. Pregnancy is a journey will ensure the safe delivery of the baby while maintaining the mother in a healthy condition. The paper will also talk about the tests that the pregnant mother will undergo during the period of pregnancy because in this period the mother faces many risks of getting a disease basing on the previous pregnancies or developing conditions. The diet that the pregnant mother uses in the period is also of vital importance and ...

A forty-three year old male with cases of irritated eyes and increasingly blurry vision. The man also reports cases of skin irritation which are at certain instances severe and cases of difficulty in breathing.

His skin irritation and difficulty in breathing stared six months ago.at the onset these complications were mild and isolated in their frequency but gradually they are becoming more persistent. Irritation of the eyes started three months ago and his vision started to get blurry a month ago.

Past medical history

Noncontributory. Family history His wife, parents, and two sisters are all perfectly healthy. His three daughters are ...

Brittani Scott

Introduction Sickle-cell disease is an illness that is multisystem, linked to episodes of progressive damage of organ and acute illness, and is among the most common dangerous monogenic disorders in the world (Weatherall, Hofman, Rodgers, Ruffin, & Hrynkow, 2005). The sickle-shape erythrocytes were initially described in the year 1910 by Herrick (Herrick, 1910) and understanding has slowly increased from that time. Together with his colleagues, Pauling (1949) keyed out electrophoretic abnormalities in sickle HbS and made up the word molecular disease in the year 1949. The genetics, as well as biophysics of hemoglobin behind the disease, have been widely ...

Question one

Microscope (Polyethylene reservoirs) ( Short rectangular capillary) plati-num wire electrode This is because the red blood cell would be clearly observed using rectangular capillary. This column would enable observation of the movement of particles hence a thorough study of the mobility of the components of the red blood cells would be taken into account. Because a person is able to evaluate or rather observed the change of red blood in the capillary column is reason enough to diagnose Martin b the disease.

Question two

HbS S molecules would be likely to clump together because of the presence of the sickle cell anemia. ...

Abstract

This paper focuses on a case study involving a patient with heart disorder. The paper answers nine questions based on the case study. The case study helps provide insight into symptoms management heart diseases.

Question 1

Both health and nutritional status of PF are poor. To start with, he has a medical history of pulmonary edema. Pulmonary edema presents with among other signs and symptoms, shortness of breath and course breath sounds. Given that PF has been complaining of shortness of breath, it follows that he might be experiencing yet another episode of pulmonary edema. Pulmonary edema can also be suspected given that heart ...

Essential minerals for children growth and the consequences of lacking them.

Minerals are inorganic solid natural substances with a defined chemical composition that are stable at room temperatures and ordered atomic arrangement. They are useful to the health, development and growth of children, therefore one ought to be cautious on the correct quantity being administered as they can also be too harmful. The essay will therefore argue the essential minerals for children growth, health, and welfare; moreover discuss the consequences of lacking them. Minerals play two major functions in the body; those pertain to the forming of the human physique, and also in the aid of bodily operations. Macro elements ...

Introduction

Type 1 diabetes is a chronic illness characterized by the body’s inability to produce insulin due to the destruction of the beta cells in the pancreas through autoimmune process, infection by viruses or idiopathic means. According to America Diabetes Association (2010) onset most often occurs in childhood at 10 -14 years of age, but the disease can also develop in adults in their late 30s and early 40s. Glycated hemoglobin (HbA1c) is the stable product of nonenzymatic irreversible glycation of the beta chain of hemoglobin by plasma glucose. Its rate of formation increases proportionately with plasma glucose levels. Since ...

Diabetes Mellitus is a group of metabolic disorders that is clarified by hyperglycemia. There are many forms of this disease and the reason for hyperglycemia may be either reduced insulin secretion, decreased glucose utilization by the tissues, and increased glucose production. Diabetes causes many secondary physiological changes in the body leading to diverse affects on different organ systems; as well as being a burden to the patient and the healthcare system as a whole. Diabetes Mellitus is the leading cause of end stage renal disease as well as the leading cause of non-traumatic limb amputation and adult blindness. In the future it ...

The patient was a 24-year-old black male who was brought to the emergency room via an ambulance on June 21 at 03:50 pm. The report indicated that it was a pedestrian versus vehicle accident. The state of the patient reported included acute lung injury, pulmonary contusion, deep road rash extending over right side of axillary region to the abdomen, deep avulsion to the right hip area and exposed muscles. Trauma alert team and the respiratory therapist were called to the bedside. The patient developed respiratory failure and immediately was intubated by the respiratory therapist with an endotracheal tube size 7.5 mm. ...

Introduction:

Carbon dioxide is generated through cell metabolism that takes place in the mitochondria. Carbon dioxide amount that is produced is dependent on the metabolism rate as well as on the relative carbohydrate, protein and fat amount being metabolized. The amount of carbon dioxide produced at rest is usually about 200 ml per minute eating a mixed diet (Arthurs &Sudhakar 2005). Carbon dioxide is one of the main products that are released following metabolism and the level of it in the body is highly regulated. This paper aims at discussing the production and transport of carbon dioxide from the cells through ...

Her problem of Hypertension was diagnosed almost 6 years ago when her blood pressure remained consistently on the higher side on 4 consecutive visits to the clinic. It was consistently high in the range of 160/90 mmHg. Almost a year ago, she was also detected with microalbuminuria during her annual screening of urine. At that time, 1,943 mg/dl of microalbumin was detected in her urine sample.

Subjective

She has come to the clinic today for her regular checkup and follows up visit for the diabetes and hypertension. She is a house wife. And has three children.

Objective

She got an initial ...

Introduction:

Carbon dioxide is generated through cell metabolism that takes place in the mitochondria. Carbon dioxide amount that is produced is dependent on the metabolism rate as well as on the relative carbohydrate, protein and fat amount being metabolized. The amount of carbon dioxide produced at rest is usually about 200 ml per minute eating a mixed diet. This results in the utilization of about 80% of oxygen and gives respiratory quotient of 0.8 (Arthurs & Sudhakar 2005, p. 207). Carbon is one of the main products that are released following metabolism and the level of it in the body is highly ...

Management of Diabetes Mellitus Type 2

Argumentative essay Management of Diabetes Mellitus Type 2

Introduction

Diabetes mellitus is one of the most common chronic conditions, affecting about 7% of the Australian population (Lamoureux et al., 2012). Many of the lifestyle habits and choices of people today – obesity, sedentary lifestyle, cigarette smoking, and hyperlipidemia, and low-fiber diet – are modifiable risk factors for diabetes (Australian Institute of Health and Welfare, 2013). Environmental and social determinants for diabetes include family history, ethnic background, highly stressful lifestyle, low socio-economic conditions, adverse childhood experiences, and malnutrition in early childhood (Raphael et al., 2010). The management of diabetes includes, apart ...

Abstract

In order to understand the effect of hemoglobin count or iron metabolism on Alzheimer’s disease is one of the purposes of this study. The other purpose is to see if these differences in the way iron is metabolized or the difference in hemoglobin count among ethnic groups effect the way they acquire Alzheimer’s over time. The most common effect of AD is dementia which is one of the most common effects of Alzheimer’s disease and tis is the loss of the ability to mentally process normal day to day activities. Dementia can last for a long time ...

Introduction

An article published by the Cochrane Collaboration and posted in the Cochrane Library in 2012 caught my attention. The article stated that no quasi-randomized or randomized clinical trials of gene therapy for sickle cell disease have been documented. The article further stated that no conclusions and recommendations are attributed to the application of gene therapy on sickle cell disease (Olowoyeye & Okwundu, 2013). This statement inspired me to evaluate the current developments in gene therapy that targets sickle cell disease. Sickle cell disease is one of the oldest genetic disorders and yet few attempts have been made to develop gene ...

Analysis of Culture Cell KU812F with Three Protocols

Abstract Protein analysis for cancer cell research has been found to be extremely reliable. The culture cell KU812F (chronicle myeloid leukemia cell line) was used for this laboratory. Globin gene switching was observed by evaluating the gene expression in the cells. Gene expression and protein folding were provoked. Gene expression is the process of transcribing DNA to cDNA and then used qPCR to study gene expression. cDNA was translated into mRNA which in turn is translated into a protein. mRNA concentration was analyzed. The three protocols were Reverse Transcription Polymerase Chain Reaction (RT-PCR), Enzyme-Linked immune sorbent assay (ELISA), and ...

Abstract:

Diabetes is a significant problem in health care. The problem is growing significantly as worldwide populations are getting older and more obese due to a variety of reasons. The paper reviews current pathophysiological and treatment literature regarding the treatment of diabetes. It focuses primarily on gut hormones and the physiological effects they produce in the disease as well as on surgical methods of diabetes resolution that has varied pathophysiological bases. Novel ways of treatments do not always have fully elucidated rationales for how they work, as bariatric surgeries may have multiple effects on the pathophysiology of the disease and this must ...

About 25.8 million Americans are diagnosed with diabetes and 90-95% of cases are type 2 or non-insulin dependent (CDC, 2012). Diabetes mellitus is a very complex illness brought about by the interplay of genetics and unhealthy lifestyles and affecting multiple organ systems (Strayer & Schub, 2012). It is one of the leading etiologies of stroke and cardiovascular disease and thus remains a significant cause of morbidity. A complex etiology requires equally complex management focusing on better lifestyles, adherence to medications and self-monitoring one’s health status. Patient education is then an indispensable component of care and must be supported by research evidence ...

Further, on one occasion while playing golf, she complained of light-headedness and therefore had to be rushed to the emergency department of a hospital. Though her temperature was within normal limits, she had an elevated heart rate and an elevated respiratory rate, and a low blood pressure. These findings are also indicative of anemia.2 Ms. A states that the heavy menstrual flow she had during her menstrual periods had been a long standing problem (past 10 to 12 years) and that she takes aspirin four hourly for six days during menstruation. Besides, she also takes aspirin during the hot season of summers ...

Epidemiology of Thalassemia among the population of Malta

This discussion is about epidemiology of thalassemia in Malta. Thalassemia is the given name of a category of genetic blood confusions typify by anemia because of augmentation of red blood cell destruction (Barnes, Plotnikoff, Fox, and Pendleton, 2000). Hemoglobin, it is the conducting of oxygen of the red blood cells dwelling by the two diverse proteins which are the alpha and beta. In case that the body doesn’t construct sufficient with these two proteins, the red blood cells is inadequate and cannot bring enough oxygen (Sembulingum K. Et Al, N.D.). It is a severe with a more than few of health ...

Child and adolescent health issues require extra concentration due to the fact that an early disease can lead to an improper growth which may impact the entire life of a person and therefore it is important to ensure that childhood and adolescence diseases are looked after with extreme care in order to improve the quality of life and the growth of the patients. Sickle cell anemia is one of the widely studied subjects today, considering that it can cause acute chronic conditions which include severe pain and organ dysfunctional ties and has a high fatality rate. This disease is also known ...

Digestion in human beings and other animals is overly dependent on the action of enzymes; in their basic form, enzymes are protein materials that act as catalysts with the ability to produce certain chemical changes. Digestion of food substances usually begin in the mouth. The glands in the mouth produce enzyme salivary amylase (which acts on starch changing it into sugar) and lingual lipase (which kicks off the digestion of lipids) (Chiras 109). The stomach n its part, produces two enzymes, pepsin that breaks down proteins into peptides (Chiras 109). While there are no enzymes produced in the large ...

Regulation of body pH occurs either through pH regulation or pH compensation. Regulation occurs as a combined effort of buffer systems, and respiratory and renal systems. Normal metabolism produces acidic wastes, for example, carbonic and lactic acid. These products increase acidity of body fluids and cause a shift in body pH away from the normal alkaline nature. Buffers help to prevent the shift towards an acidosis, and hence maintain pH of the blood and the body. Buffers also facilitate maintenance of narrow pH ranges of body fluids. Maintenance of this narrow range is crucial since biochemical reactions are affected by concentration ...

Renal compensatory mechanisms

Severe anemia causes the redistribution of blood supply to vital organs such as the brain and heart. This results in a decrease in renal blood flow causing the activation of the renin-angiotensin-aldosterone-system. Activation of this system results in increased production of aldosterone by the adrenal glands. Aldosterone causes increased retention of salt and water by the kidneys. This compensatory mechanism increases blood volume and renal blood flow without altering tissue hypoxia in other organs (Gaspad, 2005 as cited in Coyer & Lash, 2008).

Pituitary gland

The decrease in renal blood flow also stimulates the production of anti-diuretic hormone which increases ...