Essays on Sera

Introduction

Zika virus also termed as ZIKV is a known to have gained worldwide attention, especially in the USA, South East Asia, and Australia. The Zika belongs to the Flaviviridae family which comes under the genus Flavivirus (Wikan & Smith. 2016). The Zika virus is spread though day time mosquitoes belonging to the Aedes family. Some of the most common mosquitoes to contain and spread Zika include A. aegypti and A. albopictus. The name of Zika originated in 1947 where it was first isolated from the Zika forest in Uganda. Based on evidence, the Zika virus was associated with varying viral ...

Overview: Overview: Antigen-antibody reactions are commonly used in immunological assays. In a traditional agglutination assay, the end product is a visible antibody-antigen complex that settles as visible particulate matter in the solution. In other cases, the reaction is invisible and wants the use of a specific enzyme or isotopic probes that can amplify the signal created by the antigen-antibody reaction, so that they can be detected with the naked eye or an ELISA/RIA reader1. Hemagglutination is a visible antigen -antibody assay in which soluble antibodies react with antigen on the surface of (red blood cell) RBC to form a ...

RESULTS

Section 1 All samples were found to be positive for the anti-Ro antibody with higher than 240 IU/ml, except Sample ID # 13 and 32, which showed lower concentrations (Figure 1.). These samples also exhibited occurrence of Smd and Dn respectively, albeit at low concentrations. Sample Id# 12 and 20 also showed presence of anti-La antibody. The autosera of Patient Id # 32 suffering from SS displays a faint 52kd IgM band, which is representative of 52kd anti-Ro antibody and is fainter in ethanol treatment sample. Patient ID # 42 expressing a higher than 240 IU/L of anti-Ro antibody in the clinical ...