Essays on Merck

Merck and Its CSR

Facts River Blindness is a disease affecting people in some of the poorest countries in the world, in Africa and Latin America. In 1978, an estimated 340,000 people have gone blind and about 18 million were infected with the disease. Dr. William Campbell discovered a possible use for ivermectin: It can be developed into a cure for River Blindness. He thus sent a memo to Dr. Vagelos requesting funds to develop the new product. The problem is that the product cannot be profitable. The target communities are not among the company’s target markets. Since these communities are ...

Business Ethics

In the United States, drug companies enjoy a high-profit margin. It means that when purchasing different commodities, Americans incur high costs, unlike Canadians or Europeans. The drug industry has been noted as the most profitable sector in the economy in the last two years. The United States drug prices do not indicate a fair and competitive market since they sell only a handful of essential drugs with the aim of establishing a top selling market (Williams, 1985). Pharmaceutical companies have ethical responsibilities that contrast with that of small biotechnology organizations regarding research and innovation. For instance, CV Therapeutic is ...

Roseola also known as exanthema subitum or Sixth disease is a viral infection caused by human herpesvirus 6 (HHV-6) common in infants and young children. The pathognomonic sign of roseola infantum is the development of acute high fever and febrile seizure. Commonly after defervescence, a rubelliform eruption or rash occurs. A clinical exam is needed to diagnose roseola and the treatment is symptomatic (Caserta, 2014). To patients who are immunosuppressed, HHV-6 is a major cause of morbidity and mortality. HHV-6B can also cause CNS disease in these immunocompromised patients ("Roseola Infantum", 2016).

Pathophysiology

The transmission of the HHV-6 is airborne, ...

The question of facility planning is one of the most important when it comes to the discussion about creating or building something new. Considering correct planning it is essential to realize the changes it can bring to the authors of a project. The quality of many lives will definitely be enhanced, and this impact cannot be ignored during the planning process. This way, the result depends of many aspects, among which the facility planning can be viewed as the most important.

Steps of Facility Planning

Tips for correct facility planning are the combination of different principles. Firstly, one should provide a study of ...

Ivermectin

Abstract Ivermectin is a group of medicinal drugs under the larger group of avermectins. It was first discovered in the early 1970’s and accepted for use in the 1980’s in veterinary medicine applications and later for human conditions treatment. Biosynthesis of ivermectin is done from the primary compound avermectin and was discovered by a group of scientists who were led by Professor Satoshi Omura (Eng). The results of their research were later forwarded to the MSD research laboratories which isolated the compound avermectin from the sampled soil that was studied. Synthesis of avermectin results into eight main ...

“It’s a tough call whichever way you way you look at it.” Dr. Vegelos was moving in small circles heading to no definite destination. He was the most senior medical personnel of the state hospital besides being a research fellow at an affiliated non-profitable institute a stone throw from the main hospital. “ I suggested you give it some more time and finally things will fall into place. In this facility, we have seen and handled the most treacherous situation in comparison to this at hand at the moment. Added Dr. Campbell, who had to spend some nine years ...

Summary of Article

INTRODUCTION Altered oligonucleotides, specifically, labeled RNA serve as important tools in biochemical and biomedical research and have been commonly utilized for therapeutic and analytical purposes . Although there are many studies on post-synthetic techniques on DNA, such as by Marx et al., very few reports have described the techniques related to RNA. An efficient automated RNA synthesis with an optimal yield is a prerequisite for post-synthetic derivatization. It is a commonly accepted truth that RNA production is much more troublesome and challenging than DNA synthesis, owing to its lesser coupling efficiency in the synthesis cycle along with the requirement to ...