Essays on Malignant Melanoma

Ultraviolet light (UV light) is a type of electromagnetic radiation that is located between visible light and X-rays in the electromagnetic spectrum. It is invisible to the human eye, and has a frequency greater than that of visible light but lesser than X-rays. It has a wavelength ranging from about 10 nm to 400 nm (ISO, 2007). UV light is a part of the radiation that comes from the sun. It can also be produced artificially by electric arcs, black lights, tanning lamps and mercury vapor lamps. The name Ultraviolet literally translates to “beyond violet”, as it has a ...

Melanomas are tumors that arise from the melanocytes or the pigment cells (Mihajlovic et al. 739). A common form of melanoma is the primary mucosal melanoma that is found in the mucosal lining of the urogenital tract, respiratory tract and the gastrointestinal tract (Mihajlovic et al. 739). Primary malignant vaginal melanoma is one such type of mucosal malignant melanoma that is very rare (Lin et al. 376) and very aggressive in nature (Androutsopoulos et al. 1). The first case of primary malignant vaginal melanoma was reported in 1887 and modern literature has noted about 500 cases, globally (Chen et ...

Skin cancer or metastatic melanoma is one of the most aggressive types of cancer (Chin, Garraway, and Fisher, 2006). Understanding the physical or phenotypic alterations that occur in relation to skin cancer requires getting acquainted with its pathophysiology. Furthermore, learning the pathophysiology of metastatic melanoma can lead us to a better understanding of what may be most effective in curing the disease. Metastatic melanoma, causing approximately 13,000 deaths annually with a median overall survival (OS) period of 8 to 18 months, is considered as one of the most aggressive and prevalent types of cancer (Finn, Markovic, and Joseph, 2012). ...

Malignant melanoma is a skin disorder, which produces tumors of melanocytes or tumors of cells produced by melanocytes . The disease was uncommon in the past; however, in the recent years, the number of cases of malignant melanoma increased significantly, especially, the number of deaths due to malignant melanoma. The disease develops in radical and vertical phases. In the radical phase, the malignant cells develop in a radical manner within the epidermis, while in the vertical phase; the malignant cells intrude into the dermis cells. The lesions developed by malignant melanoma are thin, moderate or thick depending upon the depth of the ...

Every day, researchers come up with new studies that document the fact that teens are fighting shy of sunscreens. Teenagers have ignored the possible harmful consequences of not using sunscreens and continue to do so. This paper not only attempts to find the reasons of this careless behaviour of teenagers regarding sun protection, but it also explains the negative consequences of failure to adopt sunscreens in routine life. These results have been further categorized into short-term and long-term effects in order to capture the severity of the matter at hand. The excuses that teenagers find and hold on ...

Introduction

In multicellular organisms, the cell divisions occur under the control of strict control of internal and external signals. However, cancer involves an uncontrolled growth of cells. The branch of medicine that deals with the study of cancer and tumors is known as oncology. A tumor is an abnormal mass of cells that may be benign or malignant. Benign tumors do not spread to other parts of the body while, malignant tumors can spread from the original site known as the primary site to other organs establishing secondary tumors. According to their tissue of origin, cancers are classified as ...

Abstract

The analysis of literature review of this research was on the effects of tanning beds to the skin, a topic that is getting news rating because it bans the use of tanning beds in younger populations according to the current Louisiana’s new legislation. This study is predestined to review the augment that artificial tanning, as a comparative background of the skin has impacts. According to Demko, et. al., 2003, the risks of skin cancer claims, have been brought on board, concerning tanning beds being behind the increased cancer risk, though, through the research conducted, there is support and opposition ...

Immunotherapy of Malignant Melanoma Using Dendritic Cells Vaccines

Abstract 5 research papers on dendritic cell (DC) vaccines for malignant melanoma (MM) were studied. Study designs, patient-specific vaccine preparation, pulsing of DCs and survival rates from different types of DC vaccines were analyzed. Patients with stages III and IV MM were included for trials in all the researches. DCs were pulsed with TRIMEL, tumor lysate, melanoma associated antigens: gp100, MART-1 and tyrosinase. Delayed type hypersensitivity (DTH) was studied to determine effect of the antigen. A positive reaction was considered to be appearance of eythema at the injection site. Pulsed DCs were selected by cloning and selection. ELISPOT ...

Introduction

The skin is an essential organ in the human body made of a complex membrane of cells, tissues and pigments that hold the body together. Similarly, the skin color is determined by the amount of melanin, the location of melanin and melanocytes, and the presence of caretenoids (Ostler, et al., 2004). Further, the ratio between oxygenated blood and hemoglobin and exogenous or endogenous pigments, also affect the skin color. Melanin is a vital tissue in the skin and the malfunction of melanocytes system, can lead to pigmentation disorder (Rose, 2009). The malfunction of melanocytes system can amount to melanocytic nevi, a ...