Toxicity Reports Samples For Students

Article 1: Radiation Associated Brainstem Injury

The tolerance of the central nervous system (CNS) to radiation treatment is significant to patient under treatment for metastatic or primary diseases associated with neck, brain and head. In most cases, brainstem injury is graded by most widespread toxicity criterion of the Cancer Therapy Evaluation Program based on symptoms. The first grade is considered mild, the second grade is moderate and without the capacity to interfere with daily living activities. The third grade presents extreme interference with the activities of daily living while the fourth grade is life threatening. The manifestation of severe radiation therapy induced central nervous system ...

Glade Bender JL, Lee A, Reid JM, Baruchel S, Roberts T, Voss SD, Wu B, Ahern CH, Ingle AM, Harris P, Weigel BJ, Blaney SM. Phase I pharmacokinetic and pharmacodynamic study of pazopanib in children with soft tissue sarcoma and other refractory solid tumors: a children's oncology group phase I consortium report. J Clin Oncol. 2013 Aug 20;31(24):3034-43.

This study describes a phase I clinical trial of “Pazopanib” in pediatric patients suffering from soft tissue sarcoma (STS). Pazonapib is an anti-angiogenic drug. It is a competitive inhibitor of ATP molecule1,2. It competes with the ‘substrate’ ...

1. Which of the following is an antidote for benzodiazepine overdose or toxicity?a. Buspirone (BuSpar)b. Hydroxyzine (Visteril)c. Flumazenil (Romazicon)d. Naloxone (Narcan)There is one other drug overdose antidote in the above list. Name the drug and its mechanism of action. Flumazenil (Romazicon®) is another drug given to reverse the depressant effects of benzodiazepine and thus useful for overdose treatment. It acts as a competitive antagonist of benzodiazepines, having high affinity to GABAA receptors, which is the BZD binding site. This allows it to specifically target benzodiazepine and drugs with similar MOA such as zolpidem, but not other ...

Technical Fact Sheet

CHEMICAL CLASS/TYPE
Morphine is an opiate alkaloid, which are a group of chemical compounds with analgesic (pain-relieving) and narcotic (sleep-inducing) properties. Similar compounds in its class include buprenorphine, and the synthetic opioid heroine.
It is found naturally in the environment in the sap of the opium poppy plant, Papaver sominferum (National Center for Biotechnology Information, 2012).
These compounds exert their actions on the body through the opioid receptors, which are found on many different tissues. Morphine has widespread effects in the body, of which the most prominent are on the central nervous system and on smooth muscle ( ...

Report on Vinyl Chloride

Report on Vinyl Chloride
The case involves a man who went into a polymerization tanks measuring 8 feet in high and 5 feet wide. The man went into the tank alone at night, and there was no light in the pit. After 20 minutes, the man did not return, and somebody went to check him. The man was found lying in the pit. The person who was looking for the man climbed in order to get the man out, but the person was overwhelmed by the gas. The person immediately shut the open valve feeling dizzy. The person dragged himself ...

Cell culture is an in-vitro technique of cultivating cells under controlled conditions and in sterile conditions. The technique was first developed by Ross Harrison in 1907. During the process of cell culture, the cells are detached from their tissue of origin and segregated from each other, either by mechanical or enzymatic means. The detached cells are then transferred before culturing them in cell culture plate or flask. The first generation of producing cell through this method is called primary cell culture. The cells from the primary culture are transferred to a new culture plate with a fresh medium to ...

Introduction p. 3

Significance p. 4
Trend Drivers and Patterns p. 5
Impact on the Hospitality Industry p. 7
Subway: A Case Study p. 7
Impact on Future Professional Development p. 9
Conclusion p. 10
References p. 11
Chemicals in the food chain and the relevance to the hospitality industry.
1.0 Introduction:
In the past, the process of a food chain was simple; foods were eaten as they were produces due to lack of preservation techniques. While it was considered to be important, food was categorized as just a commodity (Gauther, 2012). As industrialization increased, farmers became more distant from consumers and ...

Introduction

Orthopedics refers to the branch of surgery devoted to the diagnosis and treatment of illness, injuries malformations and deformities of the musculoskeletal system (Goriainov et al. 2014). The system includes the muscles, ligaments, tendons, joints and bones. Orthopedic engineering leverages biomaterials in the form of implants such as sutures, joint replacements, bone plates and so forth. It also deals medical devices to replace damaged and defective parts of the body (Goriainov et al. 2014,"Material, Technology and Profit” 1988).
Biomaterial is termed as "Any substance (other than drug) or combination of substances, synthetic or natural in origin, which ...

Analysis of Water Quality from the Rivers Colne, Holme and Calder Flowing through Huddersfield/Mirfield

Analysis of Water Quality from the Rivers Colne, Holme and Calder Flowing through Huddersfield/Mirfield

Introduction

It is a truism that water is a valuable resource. Rivers are among the major suppliers of freshwater resources for humans and other terrestrial organisms. Thus, without rivers humans could not have survived. The importance of river systems has been elucidated even during the rise of the Egyptian Civilization. The Nile River for instance has provided humans with food, drink, fertile soil and even a site for settlement (Hassan and Al Rasheedy, 2007). The ecosystem services that the river provide to people since time immemorial include water supply ...

Abstract

The purpose of our experiment was to visualize the effect of light intensity on oxygen production. In the capacity of a test subject we used algal cultures. For these researches we used the Winkler method of titration. Our experiment results showed that there is an effect of light intensity on oxygen production. Our research has a great significance for agriculture, biochemistry and biophysics.

Introduction

Photosynthesis is the metabolic process by which plants trap solar energy, convert it to chemical energy, and store it in the bonds of organic nutrient molecules, such as glucose. Nearly all types of plants and algae, as well ...