Genetics Research Proposals Samples For Students

Specific Aims

Activation-induced cytidine deaminase (AID) encodes a DNA-editing deaminase, which is a group of the Cytidine Deaminase family (Bello). This protein is concerned in somatic gene conversion, hypermutation, and class-switch recombination of Ig (immunoglobulin genes). Activation-induced cytidine deaminase (AID) has been expressed in B cells at germinal center and starts the events, which lead to class switch recombination of immunoglobulin genes and somatic hypermutation. Additionally to this primary responsibility in immune diversification, deviant targeting of Activation-induced cytidine deaminase activity leads to translocations and point mutations of oncogenes linked with B-cell lymphoma. Lately, AID has been related in active DNA demethylation (Sariah).
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Among the many problems plaguing society today, one of the most prominent is hunger. Every day, all over the world, people are starving because there is not enough to eat. While one of the primary reasons for this is, they do not have enough money to afford food; the secondary issue is there simply is not enough food. Humans survive on livestock, natural, ad synthetic nourishment in order to survive. Those attempting to survive predominantly from crops experience the most hunger. Crops can suffer, and even die, for many reasons. Weather, pestilence, and even the pesticides designed to keep ...

1. NAME OF STUDENT:
2. TITLE OF PROJECT:
3. SUPERVISORS:
1. TITLE OF THE PROJECT

2. DETAILED DESCRIPTION OF PROPOSED PROJECT:
(a) Aims and objectives:

This proposal mainly aims to:

- develop a system of strategy to decrease the exposure of patients and workers in X-ray radiation;
- Make a proposal on the determination of the effect of the X-ray on cellular metabolisms of reproductive cells of sample populations;
- Develop a method of procedure to lessen the X-ray exposure among the patients and workers;
- Test the effectivity of the developed method; and,
- do a comparative study with direct ...

Research Plan

Introduction
Toxin-antitoxin (TA) systems incorporate pervasively in prokaryotic genomes that have also been suggested to perform a role in numerous critical cellular operations (Van, & Bast, 2009). These systems characteristically comprise of a two-gene operon encoding a toxic protein molecule which aims at an important cellular purpose and an antitoxin that connects to and hinders the toxin. Control of toxin action is attained via differential constancy of the stable toxin as well as the unstable antitoxin (Kamada & Hanaoka, 2005). In several occasions, the antitoxin also operates as a transcriptional autorepressor of the operon, whereby the degradation of the antitoxin leads to transcriptional introduction ...

Abstract

The red squirrel is one of the modern wonders of evolution. The squirrel has a surprisingly red toned fur as opposed to the conventional grey squirrels. The red pigmentation of the fur of this squirrel can be attributed to a process known as melanism. This is the process through which darker pigmentation occurs. This dark pigmentation can be expressed either in skin or in feathers or in fur. There are a number of factors leading to the development of the red squirrel for example habitat. The red squirrel lives in Europe and primarily in Denmark. The squirrel also lives on top of ...

Abstract

A-kinase anchoring proteins (AKAPs) are a group of structurally varied scaffold proteins which are found to regulate the PKA pathway by localizing the protein kinase A and some specific enzymes at sub cellular level. So far several of the AKAPs have been found to play critical role in the regulation of phosphorylation of several PKA dependent substrates which are necessary for the modulating the cardiac function. Abnormalities in these AKAPs genes have been found to cause various forms of cardiac disease. The most prominent AKAPs are the AKAP9 and AKAP13. Mutations in the AKAP9 gene has been found to be ...

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Introduction

Genome imprinting is the latest technique that has genetically modified the face of infertility; it is an epigenetic phenomenon through which the parental origin of a gene is determined based on its expression. 1 There are a vast number of genes in mammals that are marked with their parental origin, and the result of this phenomenon is a single parental allele. These marked genes are known as “imprinted.” They rely on the epigenetic machinery determining their parental identity and maintaining their origin-specific gene expression. There are 100 imprinted genes estimated in human and 200 ...

In archeology, DNA analysis has been used as an investigatory tool since it became available to scientists. DNA analysis, which is a constantly developing and expanding field, has allowed archaeologists to precisely and decisively obtain results that solve archaeological, historical, and evolutionary questions. Unfortunately, the methods for using ancient DNA analysis tend to destroy the samples from which the DNA is extracted. The results can easily be affected by external contamination as well, which requires the research to be conducted within specialized laboratories by trained laboratory personnel (Arandjelovic, Guschanski, Schubert, Harris, Thalmann, Siedel, & Vigilant, 2009).
DNA analysis has been ...

Abstract

The ecological settings in an ecosystem change from time to time. The changes in the ecological settings are brought about by a plethora of factors. Through evolution, the organisms that live in the ecosystem also change to adapt to the aforementioned ecological changes. The adaptation of the organisms to the ecological changes yields variations because different organisms and even organisms of the same species are exposed to the elements to different levels. Man has a significant role to play in the ecological changes. Through his economic activities, the effect on ecosystems has been both positive and negative. Urbanization as ...

The characterization of leukemia depends on the synchronous use of different systems. Histomorphology and Cytomorphology are consolidated with multiparameter Flow cytometry and cytochemistry to relegate the sample to the right entity. Chromosomal investigation, regularly supplemented by PCR and fluorescence in situ hybridization is beneficial. Leukaemias are as of now analyzed using combination of morphological examination, Immunophenotyping, cytochemistry, molecular genetics and cytogenetics. The World Health Organization (WHO) characterization for AML expands the criteria utilized as a part of the FAB system. Immunophenotyping has a key part in recognizing negligibly separated AML and ALL, for detection of AML, and also in the classification ...

INTERGENERATIONAL NATURE OF CHILD MALTREATMENT

(Name of Student)
INTERGENERATIONAL NATURE OF CHILD MALTREATMENT

Introduction

Intergenerational child maltreatment has been a taboo topic in previous research on child abuse with very little research undertaken on the topic despite the gravity of the issue in modern society. Intergenerational child maltreatment will form the topic for this research study, with exploration of the forms of child abuse and to examine the patterns of child maltreatment and adaptive coping to the numerous forms of child abuse among survivors of the vice. The hypothesis for this research will therefore be: experiencing more types of abuse would determine the relation between ...

Abstract

The purpose of this paper is to understand the role of the family in the psychological development of an individual. As family contributes genes and the immediate environment into which a child is born and reared into adulthood, it's influence on the individual’s psychology cannot be denied. While certain characteristic of psychology in the context of the family are flexible to change, few characteristics are inflexible. An open minded approach is undertaken to explore the influence of family, and to present different perspectives that can be applied for a better understanding of the topic. The context of family ...

Abstract

The main purpose of this research is the provision of an overview about the child obesity, its causes, physiological and social changes, the existing advancements in childhood obesity, and prevention and intervention s of this problem. Attaining a complete impression about the factors linked with obesity in kids is really significant in developing the highly effective strategies of intervention. Community and family based intrusions have produced positive outcomes in order to reduce the level of BMIs and an improvement of the risk factors of MetS s. Inclusively, in the USA an increased level of obesity interventions and continuous initiatives ...

The Bayesian method, also known as Bayesian method, is an inferential rule that is commonly used whenever an update is required within any probability estimate (Cohen et al. 12-57). The estimates are done on hypotheses whenever additional evidence is in the process of acquisition. This technique is majorly used in statistics and more especially mathematical statistics. In most of the cases involving the usage of Bayesian method requires, that it be derived through statistical methods. The derivation is usually automatic and ensures that the method well in combination with other competing methods that could have otherwise been used. This ...

Introduction

Alcoholism has been a persistent problem affecting the American family, with approximations of up to 18 million Americans going through alcohol related problems (O’Farrell, et al, 2003). There are many cost effects accompanying the alcoholism problem, both physical, emotional and economic. The vastness of the costs of alcoholism cannot be over emphasized, as they affect not only the alcoholic but close family members, friends, colleagues and even the state. Statistics indicate that about 1 million adult Americans seek treatment for alcohol-related problems each year (O’Farrell, & Rotunda, 1997),

Specific aims

The most popular and widely used treatment method for alcohol ...

OVERVIEW

In the terminology of the WHO, AIDS is a viral disease that prevents the body to fight against infections and cancer ("HIV/AIDS", 2016). AIDS infected people are easily affected a large number of unusual and life-threatening diseases. These diseases are often treatable; however, successful treatment based on immune deficiency is caused by a virus there.
The causative agent of AIDS is HIV (human immunodeficiency virus). The name was adopted in 1986 as a term to describe the virus that causes AIDS. This allows the name itself to distinguish AIDS from other retroviruses and evidence offline. This virus was known ...

Abstract

Drug use is a major public health problem in society affecting everyone in society either directly or indirectly. The cost of drug abuse in society is very high, with many illnesses, accidents, crimes and deaths associated with drug abuse. Drug use is influenced by a number of factors, especially during adolescence. This is the stage in a person’s life where they are more likely to expose themselves to risky behavior and experimentation. Furthermore, peer pressure is high during this developmental stage with many adolescents seeking to fit in with their peers. In order to reduce drug abuse, it ...

Introduction

The total number of patients with cancer keeps soaring globally with around 14 million cases diagnosed by 2014. Each year, about 8 million people die of cancer-related illnesses globally. There are quite some remedies that have been proposed to mitigate in the cancer menace. This study is focused on cancer treatment by curcumin through tyrosine kinase inhibition. Curcumin is the primary coloring agent found in turmeric, a tuber of the herb Curcuma longa Lin. It has widespread use as a flavoring agent (Aggarwal and Bokyung 87). It is also well known for its medicinal value commonly used to suppress ...

Introduction

a) Brassica rapa.
The brassica rapa is a plant species that belongs to the genus Brassica and is one of the 51 genera in the tribe brassicae of the crucifer family (also known as the mustard family) (Rakow, 2004, pg.1). Within this family, there are the other 37 different members that provide edible seeds, flowers, stems, buds, and leaves (Rakow, 2004, pg.1). Based on their morphological characteristics there are three distinct groups of B. rapa. These include the oleiferous (oil-type rape) such as the Canadian Polish rape, the leafy-type B. rapa that includes the chinensis group, and the rapiferous-type ...

Dissertation Submitted in Partial Fulfillment

Public Health
November,2014
Abstract
Type II diabetes has negatively influenced millions in the United States. Adverse impact of type II diabetes in children is ever increasing and needs some serious strategic and professional input from nurses deployed at schools. Unfortunately, the sensitivity of diabetic issue is never addressed appropriately. Moreover, the lack of research on the topic has also resulted in a significant increase in childhood type II diabetes. The research indicates that controlling type II diabetes in children is possible. School nurses employing the knowledge of physical exercises, dietary plans and emergency response can readily ...

The Florida panhandle lies on a strip of land that measures 320 km by 160 km. It borders Georgia to the North, Alabama to the west and the Mexico Gulf to the south. Geographically, this place is significant because of its role in promoting biodiversity. The strip’s biodiversity has been termed as being extraordinary.
Florida panhandle has a unique and amazing natural history. Together with its surroundings such as Mississipi and the Gulf Coast, this place remains a mystery. To date, the place is not known by many people. Within the boundaries of this region, there are more native animals ...

a) Background and Significance
Type 2 Diabetes Mellitus is a chronic disorder characterized by two main features: high blood glucose level (hyperglycemia) and insulin resistance. The disorder was formerly referred to as non-insulin-dependent diabetes mellitus. The pathophysiology of type 2diabetes is progressive, characterized by decreased insulin sensitivity, deteriorating cell function, and decreased incretion function (Phielix and Mensink, 2008; Misra, 2008).
In human studies, people with type 2 diabetes have a decreased PGC-1α expression compared to healthy subjects (Wagner et al., 2008; Cantó and Auwerx, 2009; Kang, 2012). The skeletal muscles of people with type 2 diabetes and those of their ...

Introduction

It goes without saying that life without good health and peace is of no relevance. The very purpose of living is defeated if there is an absence of good health that can sustain the need of life, learning, and future challenges. One of the challenges of modern times is deformities at the time of birth. According to Lannucci (2000), "Birth defects are abnormalities that are present in an infant at birth. They include visible, structural abnormalities as well as inherited disease" (P. 7).

Statement of research

The purpose of this study is to identify the elements and features of birth defects, and ...