Antigen Research Papers Samples For Students

Immunology Disorders

The immune system is responsible for protecting the body from various parasites, bacteria, virus etc. that try to destabilize the homeostasis. Naturally, the immune system is considered one of the most important mechanisms that help us recuperate from diseases. When the immune system malfunctions and starts destroying self-cells, it leads to certain disorders. In other circumstances, the immune system may be suppressed and fail to kill disease causing cells. Here we will discuss a few disorders of the immune system.

HYPERSENSITIVITY TYPE I

Allergy or hypersensitivity type I is also known as allergic reaction or intolerance, in this scenario the immune system creates a ...

The human immune system is a proverbial double-edge sword. On one had humans depend on the immune system, and on the other hand there are diseases as a result of its improper function. These diseases due to its disorder in its function can range from immunodeficiency states to hypersensitivity . Put in simple terms, the disorders range from doing too little to an overreaction of the system. There disorders will be considered under the following heading: immune mechanism of tissue injury, autoimmune diseases, and immunodeficiency diseases. Before we go into the details of the diseases, we would like to describe what the ...

Immunogenic cell death: the role of SAGE

Immunogenic cell death: the role of SAGE

Introduction

Millions of cells are always being removed in the human body not only to regulate and coordinate the body’s biochemical pathways but also to keep the cells healthy. This particular systematic removal of cells occurs through a selective mechanism called cell death or apoptosis process. Apoptosis is not a new concept in the understanding of the biological workings of the body. This homeostatic death of body cells has been defined as a tolerogenic or a non-immunogenic event for many [1]. However, new discoveries have unearthed the existence of a different concept ...

Immunogenic Cell Death: The Role of RAGE

Introduction
Millions of cells are always being removed in the human bodyin order to regulate biological pathways and keep cells healthy through a particular mechanism called cell death or apoptosis. Through apoptosis, such homeostatic death of cells has been defined as a tolerogenic or a non-immunogenic event for many years [1]. However, during the past few years, scientists have discovered the occurrence of a different concept of cell death – immunogenic cell death (ICD), where the death of a cell stimulates a response from the immune system against antigens of a dead cell, and this mechanism of cell death may ...

Targeted therapies that include small molecule inhibitors and monoclonal antibodies have considerably altered the cancer treatment over the past several years. These drugs are currently a part of therapy for several widespread malignancies, including colorectal, breast, pancreatic, and lung cancers, as well as leukemia, multiple myeloma, and lymphoma. The action mechanisms, as well as toxicities of targeted therapies, are different from the action mechanisms of traditional cytotoxic chemotherapy. Targeted therapies are usually better endured than traditional chemotherapy, although they are linked to a number of unfavorable effects, like cardiac dysfunction, acneiform rash, proteinuria, thrombosis, and hypertension. Small molecule inhibitors are acted ...

1.0 Introduction
Serological blood grouping has been used successfully for decades to ensure safety in blood transfusion. However blood incompatibility continues to be a significant challenge in transfusion medicine reflecting the inherent limitations of the hemagglutination based serological blood typing. Some of the limitations of serological blood grouping include weak reactivity of some antibodies that are clinically significant; weak expression of some red cell antigens; the subjective nature of the available tests and lack of universal methods of detecting and identifying antibodies. In addition there are several issues related to the reagents used which include the wide variability of ...

HCV or Hepatitis C virus infection has over 5 million people affected in US (Chak, et al., 2011) and over 120 million people worldwide hence a global health problem. This virus belongs to Hepacivirus genus and Flaviviridae family (Lindenbach, et al., 2007) with six genotypes and with more than seventy subtypes. In approximately 85% infected individuals it may be unresolved, hence representing a significant hepatocellular carcinoma and liver cirrhosis cause. It is viewed as commonest cirrhosis cause and chronic liver disease in the world. It also represents the main liver transplantation cause in USA, Europe, and Australia (Thimme, et ...

Hepatitis type B viral infection is a common and serious disease that is caused by the hepatitis B virus (HBV). HBV is a DNA virus with partial double strands and belongs to the Hepadnaviridae family. One-third of the world’s population is believed to have been infected by HBV of which 6% have chronic HBV infection. Depending on the rate of infection and carrier rate, the world is divided into low, medium and high endemicity regions (Franco et al. 75). The HBV resides in the bodily fluids of an infected individual and is transmitted via the same (Aspinall et ...

Abstract

Organ transplantation is an important life-saving procedure for those people, who have some problems in their organs. However, the problem of organ transplant rejection is an important issue in this case. In this problem, patient’s immune system starts rejecting the organ as a foreign body. This problem of rejection of the organ can be acute or become chronic. Several diagnostic procedures have also been developed to reduce the problem of rejection of an organ. Scientists have done a lot of research in this regard. Acute rejection needs immediate care. In order to reduce the problem, specialists will check the area ...

UniversityRheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disease more common in women than men. It is an inflammatory disorder of the joints especially in the hands and legs which becomes chronic over time. The joints become tender and cause inflammation that could lead to serious disability which might also lead to death in some cases (Aletaha et al, 2010).

Etiology of Rheumatoid arthritis

The etiology of the disease has not been clearly understood so far. RA condition manifests itself when the components of the autoimmune system losses control and attack specific tissues in the body as they fail to distinguish between the tissues in ...

Definition and history of stomach cancer

Stomach cancer also called gastric cancer is a disease that is characterized by the uninhibited proliferation of abnormal cells in the tissues lining the stomach. These cells are abnormal in the sense that genetic mutations render them autonomous hence they are not under the control of growth regulating signals. Gastric cancer used to be the second most prevalent cancer but sharp declines have been seen in its rate in the developed countries especially over the second half of the last century, for instance it is the fourteenth most common malignancy in the United States. However, the same cannot be said ...

Multiple sclerosis is an autoimmune disorder, which affects the central nervous system. It was first described as a separate disease in 1868 by Jean-Martin Charcot (Compston and Coles, 2008). The average prevalence of the disease globally is 30 people from 100000 (Milo and Kahana, 2010). However, the incidence of multiple sclerosis varies greatly depending geography. While in the African countries it happens comparatively rarely, its frequency is increasing consistently in Asia and America. In Europe, multiple sclerosis happens with the highest rate in the world. There are four clinical forms of multiple sclerosis (Compston and Coles, 2008). Relapsing-remitting MS ...

Vaccination is the application of antigenic material, also known as a vaccine, in order to trigger the immune system of a person to create adaptive immunity to an infective agent. Vaccines can preclude or improve morbidity from disease. The vaccination’s efficiency has been broadly analyzed and confirmed. For instance, the HPV vaccine, the influenza vaccine, as well as the chicken pox vaccine (Fiore, Bridges, & Cox, 2009; Chang, Rinas, Schmitt, & Smith, 2009; Liesegang, 2009). Vaccination is regarded as the most effectual way of preventing communicable disease. Widespread immunity on account of vaccination is mainly accountable for the global obliteration of smallpox, ...

Introduction

The research paper is about Antigone, the play by Sophocles. The paper provides a complete overview of the play. Antigone’s love for her brother and obeying the commandments of God are reflected in the paper. The stubbornness and inhuman acts of King Creon are also clearly revealed. Moreover, a comparative analysis of the tragedies of Antigone and King Creon are followed by the story, and Creon is proved the real tragic hero of the story.

Background to the myth of Antigone

The circumstantial events that resulted in the tragedy of King Creon begin as Oedipus arrives at Thebes looking for his real parents. To Thebes has ...