Essays on Acidosis

The blood requires a balance between alkaline as well as acid components to function appropriately. Such a balance is referred as acid-base balance. The lungs, as well as kidneys, function to maintain such balance. Whatever variation causes acid-base imbalance. High levels of acid are referred as acidosis, and high alkaline is referred as alkalosis. Metabolic acidosis, as well as alkalosis, results from kidneys problem. Respiratory alkalosis and acidosis occur because of lungs' problem (Schrier 162). The levels or concentrations of acid or alkaline are determined on a scale of pH. Acidity makes pH levels fall, and alkaline condition makes ...

Describe the underlying pathology of COPD and the common pathological characteristics of the condition. Discuss the impact these pathological changes have on normal function, including how alveolar ventilation might be different in Mr Wenham compared to a normal individual. The hallmark pathological attributes of chronic obstructive pulmonary disease (COPD) are one, poorly reversible airflow obstruction and two, a progressive atypical inflammatory response within the lungs. The abnormal inflammatory response denotes the responses of the innate and adaptive immune systems to long-standing exposure to noxious gases and particles especially cigarette smoke. Notably, all cigarette smokers have some degree of inflammation ...

Chronic obstruction pulmonary disorders and treatment options

Chronic Obstruction Disorder disease (COPD) is one the most prevalent cause of morbidity across the globe. It is a curable and partially reversible problem which is manifested by an obstruction in air flow and impaired health status. The patients who have frequent attacks of COPD have worst condition along with acute episodes of symptom exacerbation. The objective of the treatment is to avoid the symptoms through controlling it by including the lung functioning and health status. COPD is linked with abnormal inflammatory response of the lungs to noxious gases or particles. Patients below the age of 35 are at ...

This paper addresses a pharmacological management plan for Mr. NX, including consideration of possible contraindications for CAMs, prescriptive and non-prescriptive recommendations for management of acute pain and other ongoing disease processes, followed by evaluation strategies.

Pharmacological Management Plan

CAMs Contraindicated with Current Prescriptions The order of Mr. NX include drugs such Glyburide 3 mg daily with breakfast, Lisinopril 20 mg daily and Coumadin 5 mg daily. Glyburide is an oral anti-diabetic drug (mainly for diabetes type 2). Glyburide causes lactic acidosis and. Therefore, anything that may increase the risk of this side effect is contraindicated like in this case the use of ...

Based on the clinical vignette, it seems like PJ was trying to commit suicide either by benzodiazepine overdose or by consuming antifreeze. It looks like PJ tried to drink antifreeze based on the sweet smell on his breath in the emergency room. The active ingredient in antifreeze is ethylene glycol, which is a sweet-smelling alcohol. If PJ consumed the antifreeze, then that will explain that clinical finding. When ethylene glycol is oxidized by alcohol dehydrogenase (ADH), its metabolites become toxic and cause an anion gap acidosis and profound CNS depression (Fraser 242). Furthermore, these ethylene glycol metabolites can cause ...

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Pathophysiology and Aetiology

Acute renal failure or ARF means any abnormality with the function of kidneys. Kidney performs multiple functions thus ARF is also termed as acute renal injury (ARI). Now medicine and healthcare have advanced to a higher level integrated with different drug therapies and dialysis treatments though the mortality rate with such condition is still high; that is 50% of kidney patients and up to 85% of patients with other co-morbidities (Doenges, Moorhouse & Murr, 2014). The Pathophysiology of ARF includes a rapid fall in Glomerular Filtration Rate (GFR) ...

[University’s name] According to Papadakis and McPhee (2015), chronic kidney disease affects more than 20 million individuals in the United States or every one individual out of nine. Most of the individuals remain unaware of their condition till it becomes full blown and has reached end-stage. According to Mohan (2010), chronic kidney disease or formerly known as chronic renal failure is a progressive and irreversible damage to renal parenchyma leading to depressed renal function. The major issues in CKD are acidosis, azotemia and uraemic syndrome.

ETIOLOGY & PATHOGENESIS:

All nephropathic entities can eventually lead to CKD but they are classified ...

Homeostasis means highly complex interactions, which are regulated to maintain the balance within the body of humans. Homeostasis establishes optimum conditions within an organism thereby this balance is required for the normal and proper functioning of the body. To perform the division of labor Homeostasis is divided into sub categories like temperature and acid-base homeostasis. Acid base homeostasis deals with the pH of the body. Any organism’s body is highly sensitive to maintain a level of its pH such metabolic pathways exist which maintain its normal level. PH is very important to maintain as more than 70% of ...

Asthma is a chronic airway disease that is difficult to manage because of numerous risk factors and complicated by poor self-management. This is a case study of acute severe asthma triggered by viral respiratory infection and exercise in an Aboriginal female with chronic asthma. The discussion will include the diagnostic tests, patient assessment, care and interventions, medications, and nursing care performed or should have been performed. The expected outcomes will also be described.

An arterial blood gas (ABG) analysis was performed showing respiratory acidosis and mild hypoxaemia. Above normal PaCO2 and below normal pH meant the lungs could not eliminate carbon ...

Facts and Conclusion

Facts and Conclusion Before we describe what three-parent in vitro fertilization is, let us first define what in vitro fertilization (I.V.F) is in the first place. In vitro fertilization is a process wherein the man’s sperm and a woman’s egg are fertilized outside the woman’s body (Storck, 2014). Once fertilization occurs and the fertilized egg divides to become an embryo, the embryo is placed in the uterus (womb) of the woman. Pregnancy in this sense happens once the embryo attaches to the lining of the uterus (Storck, 2014). The process of in vitro fertilization is often ...

Introduction

Chronic kidney disease (CKD) is a condition in which the kidneys lose their function over time. It is a state of irreversible kidney damage. The adverse outcomes of chronic kidney disease result in kidney failure, cardiovascular disease and premature death. Effective treatment at the early stages of the disease reduces the chances of other complications. The two major causes of chronic kidney disease are high blood pressure and diabetes. The common symptoms of the disease are fatigue, swollen feet and ankles, dry, itchy skin, frequent urination, poor appetite and concentration .

Clinical Presentation

The classification of chronic kidney disease involves five stages. Stage 1 ...

Cause of Ms. S’s Diabetic Ketosis Acidosis (DKA)

Ms. S’s Diabetic Ketosis Acidosis (DKA state is one of the most extremes of diabetic decompensation since it is associated with high mortality rate. The incidence of Ms. S’s DKA, usually, occurs at 4.6-8.0 per 1000 persons-year among the patients with diabetes. The pathogenesis of the condition occurs as a result of the abnormalities associated from the combination of relative or absolute insulin deficiency (Health & Medicine Week, 2014). When the level of insulin is deficient, the increased levels of glucagon cortisol and catecholamins will automatically stimulate hepatic glucose production through enhanced gloconeogenesis and increased glycogenolysis. The combined level ...

Written Case Study – Pathophysiology II

(Location of the University) 1. Describe the underlying pathology of COPD. What impacts do these pathological changes have on normal physiology? In particular, describe alveolar ventilation in a normal individual and discuss how this might be different in Mr Wenham. (20 marks) Chronic Obstructive Pulmonary Disease or COPD is touted to be the third leading cause of death in the United States of America. In 2010, it has claimed the lives of 134,676 individuals (CDC 2013). By definition, COPD presents persistent blockage of airflow in the lungs — thus interfering normal breathing. Those afflicted with such condition generally ...

There are nearly 5 million cases of epilepsy in the United States every year. The most common and serious form of status epilepticus occurs to people with no prior history of epilepsy. About 5% of adults and 10% to 25% of children will develop this disorder every year. Infants and elderly people are at more great risk of developing Status epilepticus yearly than others1. About 1.4% of white and 1.1% of black people will develop this disorder every year compared to 0.6% of Hispanic who will have a lower rate of such incidence. About 1.23% of women will develop ...

Urolithiasis refers to the condition where there is the formation of urinary stones as well as their location in the urinary system. While the term urolithiasis refers to those stones that are in the ureter, nephrolithiasis also known as renal calculus refers to those stones that are found in the kidney, and cystolithiasis (vesical calculi) refers to the stones that are formed or located into the urinary bladder (Pearle, Calhoun, & Curhan, 2007). The urinary stones also known as calculi refer to the hardened mineral deposits forming in the kidney. The stones originate as microscopic after which they develop ...

J.K has acute kidney failure with Rhabdomyolysis. Acute kidney failure happens when the kidneys are suddenly not able to sift waste products from the blood. This results to accumulation of waste and affects the chemical balance of the blood. Rhabdomylosis is caused by skeletal muscles injury (Grau, Poch, &Bosch, 2009). The injury of the skeletal muscles results to the production of different intracellular muscle ingredients. In this case, J.K had an acute renal failure with Rhabdomyolysis because of cocaine and heroin use. Cocaine and heroin cause damage to myocyte. Damage to the myocyte leads to an entry of sodium ...

The patient was a 24-year-old black male who was brought to the emergency room via an ambulance on June 21 at 03:50 pm. The report indicated that it was a pedestrian versus vehicle accident. The state of the patient reported included acute lung injury, pulmonary contusion, deep road rash extending over right side of axillary region to the abdomen, deep avulsion to the right hip area and exposed muscles. Trauma alert team and the respiratory therapist were called to the bedside. The patient developed respiratory failure and immediately was intubated by the respiratory therapist with an endotracheal tube size 7.5 mm. ...

Abstract

The rate of diabetes ketoacidosis complication is on the rise in line with the rate of population increase as well as urbanization all around the globe. Learning how to handle this complication and maintaining the blood glucose within the suitable levels is becoming a big challenge for those with diabetes, outlining the need of educating the patients as a modality for self-empowerment, treatment which is necessary for betterment of the quality of the lives of the patients. This paper seeks to analyze a patient’s condition and describe various factors that led to associated symptoms and the effects of those symptoms. The ...

Abstract

The paper articulates the electrolyte and fluid study by describing functions and location of various body fluids and factors that affects variations in fluid compartments. These body fluids involves Body fluids involve blood plasma, mucus and lymphatic fluid, saliva and gastric juice, and other fluids such as tears, sweat, semen and vaginal secretions. The functions, regulation, sources and losses of the main electrolytes in the body are also described. The paper also outlines the basic principles of some of the processes that occur in human body such as osmosis, filtration, active transport and diffusion. In order to understand ...

- Sodium imbalance The normal range for serum sodium levels in adults and older children is 137 to 145 millimoles per litre. A person with more than 145 millimoles of sodium per litre is said to have hypernatremia. A person with less than 137 millimoles per liter is said to have hyponatremia. George’s sodium imbalance could be as a result of lung carcinoma which he suffers from. Lung carcinoma is known to cause syndrome of inappropriate anti diuretic hormone. This syndrome results in the abnormal secretion of anti-diuretic hormone. The increase in the levels of anti-diuretic hormone ...

Regulation of body pH occurs either through pH regulation or pH compensation. Regulation occurs as a combined effort of buffer systems, and respiratory and renal systems. Normal metabolism produces acidic wastes, for example, carbonic and lactic acid. These products increase acidity of body fluids and cause a shift in body pH away from the normal alkaline nature. Buffers help to prevent the shift towards an acidosis, and hence maintain pH of the blood and the body. Buffers also facilitate maintenance of narrow pH ranges of body fluids. Maintenance of this narrow range is crucial since biochemical reactions are affected by concentration ...