Essays on Pathophysiology

Abstract:

The purpose of writing this report is to determine the nature, occurrence, and pathophysiology of sleep-wake disorders after sustaining Traumatic Brain Injury (TBI) and their impact on recovery and relation with other effects of TBI, along with analyzing treatment options. It also presents in the meaning of sleep-wake disturbance or disorder, a method of assessing, sample characteristics features like time and severity of TBI after the injury occurred and control of significant impacts like pain, anxiety, depression or medications. Because sleep wake disorders found in human beings who get affected by mental illness. This will lead to many problems ...

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Introduction Cirrhosis is caused by liver injury that results in fibrogenesis and inflammation. These problems result in collapse of liver structures and significant distortion of hepatic vascular structure. This distortion leads to elevated resistance to portal blood flow as well as portal hypertension. Moreover, hepatic synthetic dysfunction is also caused as a result of these problems. Clinically, liver cirrhosis is considered as an end-stage disease that could result in death until liver transplantation is performed (Tsochatzis, Bosch, & Burroughs, 2014). Liver cirrhosis is an important cause of morbidity and mortality in most of the developed countries. In ...

Pathophysiology of Rheumatic Fever

Introduction Rheumatic Fever (RF) is the type of inflammatory disease that can develop due to untreated or inadequately treated throat infection (scarlet fever or strep throat) caused by a type of bacteria known as streptococcus (Carapetis, McDonald & Wilson, 2005). This paper is going to cover pathophysiology of the Rheumatic Fever. It will begin with the symptoms associated with RF. A description of mechanisms or processes that take place in a person infected with RF will be described. This will be followed by a discussion of the causes of RF. There is a section dedicated to the pathophysiology of RF ...

Turner’s syndrome is a genetic disorder which mainly affects female growth and development. It is also termed as gonadal dysgenesis which occurs because of the absence of sex chromosome (X). The absence of the X chromosome causes abnormal development in human females. Instead of having a pair of 46 normal XX chromosomes, females with gonadal dysgenesis develop 45,X chromosomes (Castiglia, 1997). This odd combination of chromosomal pairing results in a conflicted sex of the person, where they are neither distinguished as male or female, due to the absence of the second X chromosome that would establish them ...

A total of 57 million deaths were reported worldwide in 2008, and the majority of those deaths were caused by either non-cardiovascular diseases (36 million; 63%) or cardiovascular diseases (17.3 million; 30%) according to the World Health Organization (WHO, 2011). The highest mortality rates are associated with ischemic heart diseases and cerebrovascular diseases, which account for 45% and 29% of the cardiovascular-related deaths in men and 37% and 33% of cardiovascular-related deaths in women, respectively (see Figure 1). Ischemic heart disease is considered the most common cardiovascular cause of death as it accounts for 7.6 million deaths worldwide (Institute ...

Literature on the effect of environmental stress caused by changes in the climate is more relevant today than it has been before, especially in the context of global warming (Beniston 2010). Schulte (2014) and Somero (2010) published articles on environmental stress and climate change respectively. Reading the two articles offers an understanding of how the two variables are interrelated and the effect that they have on living organisms. The manner in which the arguments are constructed presents with various positives and negatives. This critique will highlight the positives and negatives with the help of literature from other scholars. Schulte ( ...

Diabetes is a chronic metabolic disorder, which is based on the formation of insulin deficiency and an increase in blood glucose levels. Among metabolic disorders the diabetes occupies a second place after obesity. In the world about 10% of the population suffer from diabetes, however, when one considers hidden form of the disease, this figure can be 3-4 times higher. Diabetes develops due to chronic deficiency of insulin and it is accompanied by disorders of carbohydrate, protein and fat metabolism. By interfacing with other diseases endocrinology highlights symptomatic (secondary) and true diabetes. Symptomatic diabetes accompanies diseases of the endocrine ...

Introduction

Migraine is a common type of headache disorder which is characterized by moderate to severe recurrent headache. Migraine headaches are generally severe and could last up to 3 days, wherein the pain affects half of the head but the pain is pulsating in nature. People with acute migraine headache may have suffer from sensitivity to light, vomiting, nausea, and sensitivity to smell and sound. In some cases, the pain may become severe and worsen after physical activity. In 1/3rd of patients with migraine, a short period of visual disturbance or aura occurs which is an indication that the pain ...

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Question 1: Pathophysiology of Mr. Jensen’s post-operative hypovolemia

Hypovolemia is a surgical condition that indicates the rapid fluid loss that may result in organ failures. The outcomes of the hypovolemia are mostly due to insufficient circulating volume or scarce perfusion. Often hypovolemia is secondary to hemorrhage the reason of which includes severe internal or external blood loss and GI, thoracic and abdominal bleeding maladies (Devitt, 2001). Hypovolemia involves significant fluid loss other than blood that can be further accompanied by refractory gastroenteritis and widespread burns. Hypovolemia may develop in post-surgical incidence, bone fracture, due to ...

Atrial Fibrillation

Atrial fibrillation is the most encountered cardiac rhythm disorder in clinical practice. It affects <1% of persons aged <60 years. This prevalence increases to 10% in persons aged >80 years (Amerena, Walters, Mirzaee and Kalman, 2013). Atrial fibrillation is a key differential diagnosis in patients presenting with chest pain, palpitations, shortness of breath, light-headedness, and syncope (Cruickshank, 2008). This paper will examine the differential diagnosis, pathophysiology, and paramedic implications of atrial fibrillation in relation to the case of a 43-year old male who presents with features and ECG findings of atrial fibrillation. It will first examine ...

Ebola virus disease, formerly described as Ebola hemorrhagic fever, refers to a severe illness that is usually deadly in humans. Wild animals transmit the virus to human populations where it spreads through direct contact with infected bodily fluids. Typically, the disease has a fatality rate of nearly 50% with past outbreak cases recording fatality rates ranging between 25% and 90% (World Health Organization (WHO), 2016). For example, an Ebola epidemic in West Africa reported in 2014 caused global panic because it was “the largest and most complex Ebola outbreak since the Ebola virus was first discovered” (WHO, 2016). In ...

There are many different types of virus and bacteria that can have a negative effect on the human body; some are internal, while others are external. One such bacterium is Staphylococcus, which leads to infection in many human beings. The Staphylococcus bacteria is responsible for a number of different types of infections, they are described as being spheroid shaped, gram-stain positive sometimes seen in singular, in pairs, or very often in clusters; this is often contributed to being described as a bunch of grapes (Davis 1). Human beings are most susceptible to two specific strains, staphylococcus epidermidis and staphylococcus ...

Disease pathophysiology

Definition of breast cancer Breast cancer is a malignant growth of cells in the breast. This type of cancer arises in the milk-producing glands when cells begin to divide in an uncontrolled way, forming a tumor. The most common neoplasm in breast cancer is the adenocarcinoma of the cells covering the terminal lobular unit (American Cancer Society, 2016; Stephan, 2016).

Prevalence of breast cancer

Breast cancer is the most common invasive cancer to affect women in North America, with more than 200,000 new cases each year, and worldwide, counting up more than 1,200,000. It is the second cause of cancer ...

The case study presented here demonstrates a clear diagnosis of Benign Prostratic Hypertrophy or BPH.

Pathophysiology: The disease condition known as benign hypertrophy of the prostate usually develops initially in the transition zone of the periurethral region of prostate. This zone usually consists of separate lobules of tissues lying external to the sphincter. Majority of ducts of the transitional zone of urethra lie on the lateral part of urethral wall. It is important to note that it is the point of urethral angulation near verumontanum. Near the origin of this transition zone, there are glands of periurethral region. These are usually confined in the preprostatic opening. According to a renowned researcher, majority of the ...

Delirium Case Study

Acute confusional states also known as delirium are medical emergencies associated with substantial morbidity, mortality, and healthcare burden (Bassetti, 2007). The core characteristics of delirium are acute cognitive dysfunction and inattention. Delirium can result in permanent sequelea or become chronic (Fong, Tulebaev, and Inouye, 2009). This paper will examine the case of a 64-year old lady who presents with acute confusion, disorientation, and agitation. It will identify the key information provided and other essential information that needs to be identified. It will also examine the differential diagnoses and the most probably diagnosis for the patient. It will explore the ...

Chronic Obstructive Pulmonary Disease (COPD)

Introduction Chronic Obstructive pulmonary disease also known as COPD is a group of diseases which make breathing difficult by obstructing airflow and causing other breathing related problems (Centers for Disease Control and Prevention [CDC], 2015). This disease which is described by the National Heart, Lung and Blood Institute (NHLBI) as progressive because it worsens over time includes chronic bronchitis, emphysema and asthma in some cases (CDC, 2013; NHLBI, 2013a). In developing countries, poor quality of indoor air is suspected to play a major role in the disease development and progression whereas in the Unites States, tobacco smoke is reported ...

Multiple choice questions

Multiple Choice Questions

Increased erythropoietin production Increased heart rate Increased cardiac output Enhancement in oxygen extraction The answer for this question is b. increased heart rate. A reduction in tissue oxygenation as happens in anemia stimulates increased production of erythropoietin through a complex feedback mechanism. Increased production of erythropoietin enhances erythropoiesis in anemia. Increased extraction of oxygen in anemia is a compensatory mechanism that is mediated by an increase in 2, 3-diphosphoglycerate concentrations. Increased cardiac output is the main hemodynamic compensatory mechanism in anemia that aims to increase blood flow to the body organs. An increase in heart rate ...

According to the American Association of Nursing (AACN), nursing is a professional field that entails the process of caring, supporting, and organizing health abilities, preventing ailment and harm, easing pain by diagnosing and management of people response, and supporting for the care of persons, families, societies, and populations. In the United States, for one to qualify as a nurse, he or she needs to complete an associate degree (ADN), a baccalaureate degree (BSN), or diploma program after which they are allowed to be seated for and pass the National Council Licensure Examination for Registered Nurses (NCLEX-RN). Excelling in the ...

Introduction

Osteoarthritis of the knee also known as the degenerative arthritis is a major and growing problem for the elder population all over the globe. Approximately, 27 million individuals have been reported to suffer from osteoarthritis by the Arthritis Foundation in United States (US). Women have been more commonly reported to suffer from osteoarthritis as compared to men. The prevalence of developing arthritis has been found to increase after the age of 45 . Although, mostly elderly population are most affected yet there are few evidences of young people suffering from it. Osteoarthritis is also commonly defined as wear- and- tear ...

Abdominal Pain

Acute abdominal pain is a common presenting complaint. It can be due to a range of conditions some of which are benign and self-limiting and others life-threatening medical/surgical emergencies (Cartwright and Knudson, 2008). This paper will address the issue of abdominal pain from a paramedicine perspective in reference to a 29 year old male patient who presents with this complaint. It will interrogate the provided information and identify other essential information that is needed, three differential diagnoses for the patient, and the pathophysiology of the most probable diagnosis. Lastly, the implications of the case on paramedicine practice will be ...

Question 1: Uses the correct term for chronically recurring seizures.

Answer: Epilepsy Question 2: Determines if the patient in the scenario has epilepsy. Answer: J.G. does not have epilepsy. She has only had three previous cases of seizures prior to which she had not experienced any seizures. The current cases were triggered by the cesarean section thus too early to refer to the condition as epilepsy (Ko, 2016).

Question 3: Identifies possible conditions, besides brain injury, that contributes to the lowered seizure threshold for the patient in the scenario.

Answer: Apart from brain injury, lowered seizure threshold can occur as a result of infectious illnesses such as AIDS, meningitis as well as developmental disorders such as neurofibromatosis and autism (Ko, 2016).

Question 4: Describes the pathophysiology of a seizure.

The brain and the nervous systems functions within a ...

Introduction

Diabetes impacts the body’s capacity to secrete or utilize insulin, a hormone that regulates the level of sugars in the blood. Possible complications that occur due to diabetes include heart attack, cardiovascular disease, and kidneys failure. This research paper analyzes how diabetes impacts the human body.

Circulatory system

Diabetes contributes to the disposition of fats in the blood vessels over time. The fat deposits may inhibit blood circulation and result in hardening the blood vessels, a condition known as atherosclerosis. Baoge and Tao (2015) assert that atherosclerosis is a vital pathologic cause of cardiovascular disease. Also, inhibited blood circulation may ...

A Proper understanding of the pathophysiology of diseases and conditions is essential in their treatment as well as management. Every disease has a way of affecting the normal functioning of the body. Some disorders attack the whole body while others affect specific organs. Therefore, it is crucial to study the pathophysiology of diseases. It is also essential to understand the relationship between related diseases. This helps in understanding the interactions between the diseases. This paper is set to examine the pathophysiology of pneumonia, hypoxemia, as well as thyroid cancer. Additionally, the paper analyses the relationship between these diseases.

Pathophysiology of Pneumonia

Pneumonia ...

BT an 8 year old boy was presented for check-up after developing nasal congestion, sneezing and coughing. According to her mother, the boy has been developing these symptoms regularly after play or when the house is being dusted. A differential diagnosis pointed to a huge possibility of allergic rhinitis or common cold. Nonetheless, based on subjective assessment and physical examination, common cold was ruled out since the patient was afebrile, hence ruling out the possibility of an infection. As such, the primary diagnosis for this patient was allergic rhinitis and according to Greiner et al. (2012), allergic rhinitis or ...

Hypothyroidism is an endocrine disorder that results from thyroid hormonal deficiency. In the U.S. and other regions that have sufficient iodine consumption, autoimmune thyroid or the Hashimoto disease, normally causes hypothyroidism, while worldwide, iodine deficiency is the leading cause.

Pathophysiology

Hypothyroidism can be caused by malfunctioning of the hypothalamus, thyroid, or pituitary gland, as all of these result from the same “negative feedback mechanism” (McCann, 2011, p. 496). Despite belonging to the same mechanism the hypothalamus malfunction rarely causes hypothyroidism, and when it does, it is called ‘secondary hypothyroidism’. While the malfunction of the gland is referred to as ‘primary ...

Type 2 diabetes is featured by the conflation of insulin resistance and inappropriate insulin secretion. The levels of free fatty acids increase the plasma contribution to the insulin resistance which, in turn, decreases the transportation of glucose to the muscle cells and enhances the breakdown of the fat. The pathophysiology of the disease is debated on account of the role of insulin sensitivity and beta-cell functioning. Additionally, the specific roles played by these factors are still unclear. Nonetheless, there is considerable agreement that both these factors are crucial to explaining the disease's pathophysiology. Diabetes Type II typically exists when ...

Hypertension, the chronic elevation of blood pressure, results in enhanced morbidity and mortality in the long run. However, researchers are not unanimous about the pathophysiology of hypertension. Studies over the years reveal that between 2 to 5 percent patients face elevated blood pressures because of underlying adrenal or renal disease. Rest of the patients, nonetheless, do not exhibit any clear and identifiable reason for the malady. This statistics has well persuaded medical practitioners and researchers to acknowledge the role of multiple factors that might play varying roles in different patients of hypertension. Some of the most researched factors include ...

Compare The Pathophysiology Of Chronic Venous Insufficiency And Deep Venous Thrombosis. Describe How Venous Thrombosis Is Different From Arterial Thrombosis. There are various similarities and differences between the pathophysiology of chronic venous insufficiency and deep venous thrombosis. In order to appreciate the pathophysiology of chronic venous insufficiency, it’s important to understand the peripheral venous systems which act as a reservoir and conduit system for storing blood and returning it to the heart. For this system to function properly, it needs a series of valves and muscular pumps that convey blood from the lower-extremity levels of the venous system, ...

Coursename Pressure ulcers are damaged areas of the skin, which develop due to the long-term effect of pressure or friction in the areas where the bone is close to the skin, such as heels, sacrum, ischial tuberosity, lateral malleoli and greater trochanters. The epidemiology of pressure ulcers proves that today, despite the profound understanding of them, pressure ulcers are still a serious global health care problem, which affects millions of people worldwide. For example, in the US every year more than 2.5 million people suffer from the pressure ulcers (Cuddigan, Berlowitz, and Ayello 208-215). In 2013 pressure ulcers caused ...

The purpose of this paper is to review the etiology, pathophysiology, clinical manifestations, inheritance patterns, and recent advances in disease management of cystic fibrosis. Cystic fibrosis is a progressive and lethal disease resulting from an autosomal recessive gene (Singh, Rebordosa, Bernholz, & Sharma, 2015). The major problem associated with cystic fibrosis is the repeated lung infections that over time severely damage the lungs, scar and widen the passageways and limit the ability to breathe (Cystic Fibrosis Foundation, n.d.). As of 2013, there are an estimated 70,000 cystic fibrosis patients globally with 33,000 of them in the United States ( ...

Cystic fibrosis is a chronic, progressive and often deadly genetic disease that affects the body’s mucous glands. It follows that cystic fibrosis (CF) is evident in the body’s digestive and respiratory systems, particularly in children and young adults (Flume et al., 2007). In some cases, it affects the reproductive system and the sweat glands. A CF-like disease has been known over the past two centuries, but it was in 1938 that the term cystic fibrosis was first used. CF may also be considered to be an autosomal-recessive disease. Its estimated heterozygote occurrence is one for every twenty ...

Describe the underlying pathology of COPD and the common pathological characteristics of the condition. Discuss the impact these pathological changes have on normal function, including how alveolar ventilation might be different in Mr Wenham compared to a normal individual. The hallmark pathological attributes of chronic obstructive pulmonary disease (COPD) are one, poorly reversible airflow obstruction and two, a progressive atypical inflammatory response within the lungs. The abnormal inflammatory response denotes the responses of the innate and adaptive immune systems to long-standing exposure to noxious gases and particles especially cigarette smoke. Notably, all cigarette smokers have some degree of inflammation ...

Introduction

Down syndrome is an atypical chromosomal condition. The main cause of this abnormal condition is Trisomy-21, a genetic error, where every cell in the individual’s body consists of three chromosome 21 facsimiles. The presence of additional chromosome 21 replicas results in the individual’s abnormal physical development and the related cerebral disability resulting in leukemia, cardiac issues, and distinguishing physical characteristics (Lana-Elola, Watson-Scales, Fisher, & Tybulewicz, 2011). Although, it is not possible to cure Down syndrome, the availability of various treatment options make it possible for the parents and healthcare providers to handle the patient with effectiveness.

Etiology and Risk Factors

In general, ...

Abstract

Worldwide, ovarian cancer is ovarian cancer is the sixth most diagnosed cancer and is responsible for the most deaths annually than any other disease of the female reproductive system. It has a poor prognosis because the symptoms are vague even into Stage IV of the disease. Epithelial ovarian cancer constitutes about 90% of diagnosed cases. Research has demonstrated that hormone therapy, chronic pelvic inflammation, and BRCA1 and BRCA2 germline pathogenic variants are factors in the etiology of ovarian cancer. BRCA1 and BRCA2 is also associated with breast cancer, pancreatic cancer, fallopian tube cancer, prostate cancer, and primary peritoneal cancer. ...

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Introduction

Parkinson Disease (PD) is a very complicated neurodegenerative condition including the motor and non-motor manifestations that lead to neuronal loss. Currently, only symptomatic therapies are available but nothing is known yet to prevent this degenerative process. This is a multi-factorial condition with multiple risk factors that includes increasing age, genetic vulnerability, and environmental determinants. All these factors mutually play a role in the pathogenic process of PD. Medical sciences have achieved major advances in understanding the process working behind PD development that are Nigral Dopaminergic Apoptosis, Protein ...

According to the Centers for Disease Control and Prevention (CDC), stroke is the fifth leading illness that causes death in the United States. It is described as one of the primary causes of adult disability (Centers for Disease Control and Prevention). Approximately 800,000 people in the U.S alone suffer from a stroke annually. This figure translates to one American dying after every four minutes (Caplan 19). Owing to the serious prevalence the disease represents, the illness has received requisite attention regarding prevention and treatment techniques in an attempt to reduce its incidence. As a result of its quick ...

Pathophysiology

One of the most important parts of achieving the goal of being able to meet the patient’s entire healthcare (i.e. nursing) needs is to ensure that the underlying disease’s pathophysiology is well understood by all the stakeholder groups. These groups, in this case, would include the medical and healthcare practitioners, patients, and their respective family members. It would be a lot easier to instruct a patient to have a patient undergo a prescribed healthcare routine once he understands the nature of his condition, why each procedure is being done, and how they collectively contribute to the end-goal ...

Assignment 2

PART A - (Total 15 marks)

Cephalexin and Gentamicin The mechanism of action of amoxicillin is focused on the prevention of the synthesis of the bacteria’s cell wall through the binding and inhibiting of the cell wall transpeptidases (Katzung, Masters, and Trevor, 2012). Specifically, it attaches to the penicillin-binding protein 1A found in the cell wall of bacteria. Then, the agent disintegrates the lactam ring to allow the acylation of the penicillin-sensitive transpeptidase C-terminal domain. The formation of the cross-link of the linear peptidoglycan strands is prevented by the inactivation of transpeptidases. Since the third and last stage ...

While much has been hypothesized regarding paranoia, it is of the essence to note that it mainly connotes to a condition whereby an individual develops a feeling of suspicion towards others. Precisely, persons suffering from paranoia tend to harbor the thoughts that other people are against them. In fact, paranoid individuals tend to think that other people intend to harm them (Sarkar et al., 2012). As a result, paranoia makes people develop certain behaviors aligned to being highly conscious. A reflection on the lives of every individual depicts the fact that at one time in life, an individual develops ...

Healthy behaviors play a key role in daily life. Yet, certain unhygienic practices tend to interfere with the health and induce a risk to the overall life. These practices could be high-fat diet, alcohol, and smoking. There is a need to know much about these. In such context, the present description deals with a topic “ What will kill you first, a smoking, a high-fat diet or alcohol?”.

Health -related risk factors:

A risk factor is any quality, trademark or presentation of a person that improves the probability of building up an ailment or damage. A few illustrations of the more vital danger elements ...

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Introduction

Lupus is a chronic autoimmune that can impact any part of the body resulting in a range of clinical symptoms. The affected part by Lupus may include brain, lungs, kidneys, skin, joints, blood vessels and other internal organs (Pisetsky, Gilkeson & St Clair, 1997). Lupus impacts the immune system by interfering with its capability of differentiating between antigens and normal healthy tissues. This incidence results in the misinterpretation by the immune system, and it directs the antibodies against the healthy tissues causing pain, tissue damage, and swelling. It ...

Acute coronary syndrome is an umbrella term for a group of clinical symptoms indicative of acute myocardial ischemia. These conditions include non-ST-segment elevation myocardial ischemia (NSTEMI), unstable angina, and ST-segment elevation myocardial infarction (STEMI). These conditions are high-risk manifestations of atherosclerosis in the coronary artery and significant causes of utilization of emergency services and hospitalization (Kumar and Cannon, 2009). STEMI causes 30% of all acute coronary syndromes in Australia (Harper and Lefkovits, 2010). This paper will describe the expected presentation, pathophysiology, ECG findings, pre-hospital management, and initial 24-hour management of STEMI in hospitals settings. These aspects will be described ...

Introduction

The Intussusception remains as the most common problem of bowel obstruction in children and infants which needs an immediate medical attention and could be resulting in severe morbidity in children when ignored (Jiang, Jiang, Parashar, Nguyen, Bines & Patel, 2013). The given case study focuses on the Intussusceptions faced by Jayadha, a 4 months old girl, and the given case study analyses the associated pathophysiology and nursing care plan for the child in order to ensure proper adherence to the evidence based practice. The essay will start with pathophysiology and then discuss the role of nurses in the effective use ...

Introduction

Research in lung cancer treatment can save lives and improve a patient’s quality of life. There are three main types of lung cancer: Non-small cell, small cell, and lung carcinoid cancer. Non-small cell lung cancer, such as Squamous cell carcinoma, adenocarcinoma, and large cell carcinoma make up about 85% of all lung cancers (Molina, Yang, Cassivi, Schild, & Adjei, 2008). Both environmental and genetic factors are significant in the cause of lung cancer. Chronic exposure to carcinogens, ionizing radiation, and viral infections can lead to alterations of the DNA in tissue lining the bronchial epithelium of the lungs. Furthermore, ...

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Osteosarcoma, also known as osteogenic sarcoma, is a bone tumor commonly found in the childhood and adolescence. It has been commonly reported in patients in the age range of 15 to 19 years. Incidence of the disease is almost similar for both males and females. This disease develops in bone-generating mesenchymal cells (Huether & McCance, 2013).

Causes of Osteosarcoma

Rapid local growth can result in osteosarcoma and can increase the chances of mutation. Ionizing radiation, even in low doses, can become the cause of rapid local growth. It has been reported that even therapeutic radiations for other forms of cancer ...

Background information

Malaria, a mosquito borne transmissible disease of both human beings and some animals is a pertinent disease in the 21st century which accounts for more than 650, 000 deaths annually (WHO, 1147). The prevalence of malaria is highest in the tropical and subtropical regions. Adverse effects of the disease is an equally major public health issue that affects maternal and child health. In the developing countries, malaria is a leading cause of maternal and child health. Consequentially, it is a pertinent public health disease. This manuscript offers a succinct analysis of the disease while appraising its causative agents, life ...

Finger clubbing is an important medical condition associated with various diseases. Several studies and researches have stated that it is most commonly seen and described as the condition where there is an evident enlargement of the fingers specifically the terminal segments of the digits (fingers or toes). This condition exists due to the production or overproliferation of the connective tissues in the middle of the matrix of the nail and the distal phalanx (Myers & Farquhar, 2001, pp. 341). The pathophysiology of finger clubbing has been studied by numerous scientists and health experts through the years. However, the formulation of ...

Introduction

Recently, worldwide obesity prevalence has been raised rapidly and nearly doubled between 1980 and 2014, however in 2014 more than a half a billion of adult (18 years and older) were obese (11% men and 15% women) (WHO, 2014). Obesity and overweight are defined as excess body fat accumulation that leads to health risks and comorbidities. Adult weight can be classified based on the Body Mass Index. Hence, an individual having a BMI equal to or more than 25 is regarded as being overweight, while a person with a BMI equal to or more than 30 is considered obese ( ...

Introduction:

The beliefs, the practices, and the attitude towards health and wellbeing Chinese people have unique beliefs about the causes of diseases and illnesses Traditional Chinese society: specific health practices Chinese people: emotional reaction towards diseases Chinese beliefs, attitude, and practices concerning health and wellbeing Body paragraph #1: First Main Idea The concept of yin and yang: an explanation of the pathophysiology and etiology of disease and illnesses Consumption of specific foods as another cause of diseases and illnesses The concept of yin and yang: the foundation of most diagnosis and treatment practices in the Chinese society. The concept of ...

Infection in cancer patient with febrile neutropenia: epidemiology, microbiology and management

Abstract Febrile neutropenia (FN) is characterised by a decrease in neutrophils number to values below 500 cells/ mm3 and an occurrence of fever higher or similar to 38.3ºC. It commonly occurs in cancer patients as a result of chemotherapy regimens. Chemotherapy destroys carcinogenic cells but also attacks in many cases some normal cells including essential elements of the immune system. Fever is one of the characteristic symptoms of FN and is usually associated with the presence of an infection caused by various microorganisms. Bacteria, including Gram-positive isolates (currently dominating) and Gram-negative species (dominant in the 1970s), are usually ...

Introduction

The pathophysiology of atherosclerosis involves a series of complex events that can be likened to that of a chronic inflammatory process, which results in the development of an atherosclerotic plaque. The first step in the process involves injury to the endothelial cells of the artery that results in endothelial cell dysfunction. The activated endothelial cells attract vascular smooth muscle cells (VSMC) and leukocytes, which proliferate and accumulate in the walls of the artery (Seidman, Mitchell, & Stone, 2014). These cellular components lead to the formation of a large amount of connective tissue matrix. This is the ultimate end point in ...

Pathophysiology of Chronic venous insufficiency and Deep venous thrombosis

Chronic venous insufficiency is a condition that describes a dysfunction of the valves in the upper and lower extremities or the inability of the muscles in these regions to exert the required pressure that can force the flow of blood back into the heart. Essentially, the arteries are designed to supply oxygen-rich blood to all parts of the body while the veins are designed to transport the oxygen-deficient blood back into the heart (McPhee& Hammer, 2010). These processes are enhanced by the pressure exerted by the underlying muscles within the upper and lower extremities as well as the ability ...

LEGENDS:

Smoker Heart Disease Underlying Pathophysiology The participant is a 20 year old Caucasian male. His family history shows that his maternal grandfather and father have been diagnosed with hypertension, while his paternal grandfather had died of a heart disease. Porth had indicated that the risk factors for hypertension include one's health condition, family history, and lifestyle. A family history that shows relatives with hypertension does not guarantee that one may acquire the disease. However, a family history riddles with hypertension makes one more at risk than other individuals. Increasing age, a part of an individual’s health condition, may ...

Introduction

Pulmonary edema (PE) is characterized by the accumulation of fluid in the parenchyma and air spaces of the lungs. Most often PE is associated with respiratory failure and impaired gas exchange. Globally, PE is known to be characterized by two major factors, the first is associated with the injury of the lung parenchyma which is termed as non-cardiogenic pulmonary edema. The second is associated with the failure of the left ventricle of the heart to release blood from the pulmonary circulation within the system and is termed as cardiogenic pulmonary edema (Glaus, Schellenberg , and Lang. 2010). The major cause ...

Introduction

Autism is a childhood developmental disorder that affects the brain’s normal development of communication and social skills. It is a physical condition that appears in the first three years of life and is linked with abnormal biochemistry in the brain. The causes of autism are not ascertained but autism is largely attributed to genetic predisposition and the environment. A plethora of research studies have also suspected other causative factors like mercury poisoning, diet and vaccine sensitivity among others but these factors are yet to be proven (Pubmed, 2010). Autism has a variety of symptoms depending on the level of infection ...