Eukaryotes are organisms that made up of cells that have a have a nucleus that is bound by a membrane. They also have membrane bound organelles. Prokaryotes are organisms whose cells do not have a nucleus or any membrane-encased organelles.
Both prokaryotes and eukaryotes have DNA as their genetic composition or material. Secondly, both cells are membrane bound. They both have ribosomes. They have nearly the same basic metabolism. Both cells have vacuoles. Lastly, the two cells both have vesicles.
Eukaryote cells have a nucleus while the prokaryote cells lack a nucleus. Eukaryotes have a true membrane binding the