Essays on Replication

Introduction

The paper presents a framework for the configuration of windows network infrastructure for Shiv LLC. The organization deals with the manufacture and distribution of solar panel for the consumer market. It is imperative to understand the physical structure and location of the company. Shiv LLC is branched out into three. It has offices and branches in three different locations within the country; Los Angeles, Houston and Dallas. Dallas and Houston offices host the main staff of the organization. One fact that should be taken into consideration in the proposal is the fact that the organization is growing and its ...

A Research Report Submitted by:

CHE 352 Spring Semester, 2016 Chemical Engineering Program Abstract In the experiment, many measurements were taken using the heat exchanger to observe the change in heat transfer from steam to water with respect to a change in water flow rate while trying to keep the inlet temperatures of water and steam constant. The flow rate was monitored using Brooks shorate meter and adjusted with valves. The flow rate has been veried from 1 bsm to 15 bsm. Two different control points were choose the measure the temperature of water and steam: the first one in inlet and the second ...

Article 1

a. The study (Balaraman & Mathew, 2006) presents the experimental investigation of cyclosporine production by Tolypocladium fungi. This is the experimental research. b. The authors found that the maximum production of cyclosporin was significantly (at 0.05 level) higher in glucose (8%), casein acid hydrolysate (3%), malt extract (2%), peptone (1%), and amino butyric acid (0.5%), comparing to medium with lower glucose content (4%).

Article 2

a. The paper by Irum & Anjum (2012) is a full-size research paper on experimental study of methods to enhance cyclosporin by Aspergillus terreus by mutation induced by UV and chemical mutation. b. The mutation resulted in morphological ...

1. What techniques/training will the scholarship provide? The scholarship will train people on the aspects that relate to the testing and culturing of samples used in research. Testing hypothesis will be made possible through the project. The hypothesis testing skills are needed to test the hypothesis in the study. The study will base on the ability to take records and measure outcome. The project will offer training on how to test hypothesis and measure outcome. On the other hand, the scholarship will train clients on how to collect samples, record and interpret scientific data. When the project is done, ...

The advancement in technology enabled man to create various types of intelligent robots that are now widely used by humans. These technologies, such as the evolutionary robotics, coupled with the need for people to automate daily and recurring tasks brought about the idea of creating autonomous robots. Today, intelligent robots are being beneficial in the performance of different tasks as science discovered ways to make these human creations become dependable and interactive. Needless to say, there is a shift from the previous study and design of robots from strict industrial purposes, into human friendly intents. Evolutionary robotics foresaw the ...

Abstract

The current antiretroviral drugs have been efficient in the management of HIV by suppressing the virus's replication. It has, therefore, helped in changing this virus from a deathly disease to a chronic infection. The utilization of extremely active antiretroviral therapy (HAART) calls for a lifetime prescription to prevent viral rebound by reducing the viral load to undetectable low levels. This high maintenance of treatment and the various side effects of the drugs and non-HIV related morbidity have led to the need for a better form of therapy. There has been an extensive study on stem cell manipulation done to develop gene therapy ...

The process of DNA replication at biochemical level

DNA or deoxyribonucleic acid is a biopolymer that encodes all the structures needed for the organism’s lifespan and development. In a cell it is located in the nucleus, mitochondria and chloroplasts. DNA consists of four types of deoxyribonucleotides, the sequence of which is used to store the data.

The essential characteristic of DNA molecule that allows it to pass the stored information to the next generations of cells or organisms is the way of self-reproduction known as replication. The molecule consists of two complementary chains that are held together with the help of hydrogen bonds between the complementary bases. ...

DNA (Deoxyribonucleic Acid)

Deoxyribonucleic acid, DNA, is the primary structure that carries the genetic material in cells of living organisms and some viruses. The DNA is made up of strands of nucleotides that are made up of nitrogenous bases, a phosphate compound and, a ribose sugar. The nucleotides form a ring or ladder that over lapses to form double helix strands of polynucleotides. DNA aggregates to form the chromosomes that are strictly found within the nucleus of the cell. Some DNA are found in the ribosomes outside the nucleus. In the DNA structure, the series of the bases is arranged, and the sequence in one ...

Respiratory syncytial infection is an acute viral disease characterized by phenomena of intoxication and moderate lesion predominantly lower divisions Respiratory with the frequent development of bronchitis, bronchiolitis and pneumonia. A characteristic feature of this virus is its ability to determine syncytium formation or cells in tissue culture. Replicates in tissue culture HeLa, HEp-2 and human embryonic kidney. In the external environment is unstable at a temperature of 55 ° C is inactivated for 5 min.

A study of the pathogenesis of this disease is difficult. The clinical course of the disease, both natural and experimental infection among adults, does not ...

1.A. Penicillins are β-lactam antibiotics in structure. The remodeling process takes place in the bacterial cell walls due to the presence of a layer called peptidoglycan layer, which includes the breakdown of β-(1,4) linked N-acetylmuramic acid and N-acetylglucosamine and cross-linking peptide chains . Cross-linking peptide chains provide rigidity to the fluid cell wall. Transpeptidase, an enzyme used in the breaking of peptide chains also reforms the peptide bonds after the restructuring of the cell wall. The penicillin inhibits the enzyme transpeptidase, which prevents the peptide bonds from reforming. Thus, penicillin makes the cell walls weaker, which results ...

Hepatitis is one of the most serious causes of liver disorder and dysfunction, which is responsible for one to two million deaths a year. Hepatitis can occur as infectious or non-infectious. Although major causes of hepatitis include viruses, the other common causes are autoimmune liver disease, obesity, alcohol, tobacco consumption and certain other medications and herbs. Viral hepatitis is a viral-induced necroinflammatory disease of the liver caused by one of the hepatitis viruses, namely, Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D, Hepatitis E and Hepatitis G . Hepatitis and A and E are enterically transmissible viruses, while Hepatitis B, C and ...

Deoxyribonucleic acid, DNA, is involved in the manufacturing process of all proteins in the body. It synthesizes proteins that repair and replace worn out tissues in the body. Stem cells (undifferentiated cells with the ability to differentiate) researches have shown that cells from some regions of the body can differentiate into different tissues. Therefore, they can replace worn out tissues and hence function as a repair mechanism. These cells can be induced to become tissue or organ cells. Scientists argue that perhaps the stem cells may carry out similar functions as DNA hence can replace it. This paper seeks to ...

Question 1

Non equivalent Control Group Design – in this type of quasi experimental design both the treatment group and the comparison group are compared with the use of pretest and posttest data. The researcher can confidently have her claim regarding the effect of the treatment when the above groups are similar in the pretest measures but different in the post test measures.

Non equivalent Interrupted time series Group design – in this design, the researcher looks into a sequence of observations made before and after the treatment. Treatment effect takes place takes place when sudden changes occur during the implementation of ...

1. When placed on an agar slab and incubated at 30°C for 2 days, a single yeast cell proliferates into a colony with a diameter of 2 mm containing 108 yeast cells. If the cell has a functional Ade2 gene (Ade2+), the colony will be white; if Ade2 is non-functional (Ade2–), the colony will be red. You take a strain with a mutant Ade2– at the regular chromosomal position (red colonies) and insert a second, functional Ade2+ gene near the telomere. You find that the colonies are a mixture of red and white patches or sectors. Figure 1 shows some colonies; the black regions represent the ...

Significant characteristics of a disease

Virulence is a term that describes “the capacity of a microbe to cause disease after infection”. It is a multifaceted phenomenon is dependent on the “context and nature of the interaction between the host and the microbe.” The number of fatalities that occur as a result of infection by a given pathogen is used as a measure of the virulence. Based on this parameter, the Ebola virus would therefore be considered to be highly virulent as compared to small pox. Give that research has provided better understanding of pathogens thus led to the development of potent forms of therapy; some of the pathogens ...

Severe acute respiratory syndrome is a life threatening condition that is caused by a virus from the Coronaviridae family. The SARS virus is believed to have originated from the Guangdong province of southern China before spreading to Hong Kong, Canada and the United States of America. The virus has an incubation period of 2 to 7 days but it may last up to 10 days. Like other respiratory disease, SARS is spread through direct contact; long range and short range. The major agent of transmission is the droplet nuclei. The symptoms of the disease include: fever, chills, malaise, cough, dyspnea and ...

Acquired immunodeficiency syndrome (AIDS) is a condition caused by a progressed state of infection by the human immunodeficiency virus (HIV). The retrovirus can be transmitted through bodily fluids such as blood, semen, breast milk, and vaginal fluids via the bloodstream or mucous membranes (Moss; Maartens et al.; Simon et al.). Infection by HIV typically has four stages. The first stage is acute or primary infection which may last up to a few weeks, during which the infected person may either be asymptomatic or have flu-like symptoms such as fever, rash, malaise, body aches, chills, and swollen lymph nodes. Progression of the ...

Introduction

An organizations aggressive edge lies in its capacity to create provincial and worldwide vicinity while offering and keeping up best administrations at standard or superior to anything opponents. While trying to control a bigger piece of the overall industry in solar energy assembling and circulation, SHIV LLC has three branches, Los Angeles, Dallas and Houston. Remote clients in Los Angeles need to transfer close continuous data to workplaces in Houston without hardly lifting a finger. This will likewise apply to individuals from the official and administration who need to convey administrative parts to branches without much travelling. This should be possible ...

Abstract

This paper concerns the comparison between centralized and distributed database storage and management systems. The prime objective of the study is to explore the limitations of centralized databases and databank management systems and establish the how the limitations were overcome in distributed databases and database management systems. The challenges and the solutions are based on today’s business requirements and dynamic needs of organizations. The forcers which drove the shift from centralized to distributed platforms are explored and include the emergence of client-server architecture, Internet computing, local and wide area networks and the World-Wide-Web. The advancement of major structures ...

Biology of Disease

Mode of action of;- Dexamethasone The Glucocorticoid receptors are discovered intracellularly in all tissues. They enter cells through inactive dispersion and structure a complex with a receptor protein (Rhodes & Hartnoll, 2002, P.10). This intricate then experiences an irreversible enactment and enters the cell core, where it ties to the DNA, hence prompting organic impacts instigated by these hormones, which include expanded hepatic gluconeogenesis, as well as expanded lipolysis (Ahmed, 2007, P.13). Dexamethasone is utilized to treat numerous provocative and immune system conditions, for example, rheumatoid joint pain and bronchospasm. Idiopathic thrombocytopenic purpura, an abatement in quantities of ...

The Human Immunodeficiency Virus (HIV) poses a serious threat to the well-being of people in different parts of the world. When the virus infects, body cells of a healthy individual, it weakens the immune system and makes an individual vulnerable to contracting to AIDS. In essence, this paper covers many aspects of the HIV virus including its pathophysiology, genomic factors, prevention, treatment, a comprehensive literature review among others.

Pathophysiology of the Disease Processes

Usually, the HIV causing virus binds itself onto cells often classified as CD4 alongside a co-receptor enclosed by a set of glycoproteins (Hammer & Squires, 2010). Notably, replication of DNA is dependent on an unreliable process, which ...

As an Information Technology analyst, I act, upon my mandate, to provide a network solution for XYZ LLC. The proposed network will ensure high connectivity, secure access and scalability for future expansion. Already, a WAN connectivity is in place with ample bandwidth to deliver excellent connectivity.

PROPOSED SOLUTION

businesses competitive edge lies in its ability to develop regional and global presence while offering and maintaining best services at par or better than rivals. In an attempt to control a larger market share in solar panel manufacturing and distribution, XYZ has three branches, Los Angeles, Dallas and Houston. Remote users in Los Angeles need to ...

- The stromal cells that are found in the developing gonads of tetrapods begin from the medulla from the peritoneal wall and the cortex from inter-renal blastema or mesonephric. Hence the gonads have a dual origin. - Spermatogenesis occurs in a syncytial complex because it involves the formation of sperm from undifferentiated cells that are first attached to rachis. Syncytial cell complex or syncytium result when cells with single nuclei fuse to for a cell with nucleus. Syncytial cell complex is vital in oogenesis in that it assists in the differentiation of cells. One other developmental model is vitellogenesis. - ...

TA ABSTRACT – Genetic engineering now has straight forward ecofriendly strategies to produce transformation in plasmids. The transformation process allows engineers to introduce DNa with specific desired capabilities into a host plasmid. In this way plants can be created that are able to resist a particular enemy or stressor without having to use toxics like herbicides and insecticides. The bacteria E. Coli was used to determine whether it can be made resistant to ampicillin or not. AmpR was integrated into the host cells and the tracer, GFP was used to identify expressed cells. The laboratory demonstrated that transformation by plasmids so ...

A hypervisor is a computer application that allows computers to run more than one operating system. Thus takes place through a process known as virtualization. The software “tricks” the operating system into thinking that it is the only one accessing a given hardware resource. The location of the hypervisor is in between the physical hardware and the OS and presents a virtual hardware environment to all other OS running in the machine. Hypervisors also manages the flow of information between the virtualized hardware, physical hardware and software. A hypervisor has found acceptance in both enterprise and consumer settings. Usually, a computer OS runs ...

Problem

What is the problem the study was conducted to research? Type 2 diabetes mellitus (T2DM) is a global health issue. There is an increase in type 2 diabetes in African-Americans. Lack of knowledge in lifestyle and treatment interventions has led to the increase of T2DM in African-Americans. Type 2 Diabetes is a leading cause of blindness, renal diseases and lower limb amputations. African-Americans having T2DM also suffer from high blood pressure and low glycemic levels in blood.

Why is the problem an important one for nursing to research?

Diabetes has become a serious health issue among the public. Registered nurses should have latest knowledge about different interventions for diabetes. The article is ...

INTRODUCTION

Worldwide Advertising Inc. is a new advertising firm located in Los Angeles and New York. The firm is looking to hire new IT support staff to take over IT management. Prior to that, they need their IT services configured and as such requires a solution which takes into consideration implementation and configuration of core IT services.WAI looks forward to starting with 90 employees distributed in executive departments, accounts and sales, creative media and production, human resource and finance and IT departments. Most of these staff will be located in Los Angeles with at least one person in each of the departments ...

Introduction

Most of the microorganisms naturally present in the human body are harmless commensals. However, there also exists other disease causing microorganisms known as pathogens and the mechanism by which they cause disease is known as pathogenesis. These pathogens persist or multiply within the host causing infection. Some pathogens like Pseudomonas aeruginosa are considered as opportunistic pathogens that cause disease only in patients with compromised immunity and only under certain conditions. The infectious diseases may be treated with antibiotic drugs. However, it is important to know the different types of pathogens and the virulence factors by which they cause disease ...

OVERVIEW

An international pharmaceutical company is headquartered in New York, NY and has other six operational locations. The corporate headquarters in New York has 1000 employees while the other centers have a considerable number of employees and remote workers. San Diego has 250 employees, Houston has 750 employees in central research, Madrid has 500 employees, India has 50, and London has 150 while China has 300 employees and 500 remote sales workers. There is a diverse computing department with no universal standard. There is a combination of devices and operating systems in place. There are also different data center centers in operation. The ...

Human Immunodeficiency Virus, a main cause of worldwide AIDs, belongs to the Lentivirus genus of Retroviridae family. Pathogen causes chronic type of symptoms, taking a long time of latency it constantly keeps replicating inside human body. HIV is categorised into two types, HIV-1 and HIV-2. The genome of this retrovirus consists of two single-stranded RNA molecules. Though, both are involved in AIDS, HIV-2 seemed less virulent and demonstrated more frequent connections with the disease of central nervous system (Fanales-Belasio et al. 5). Like other retroviruses, the genes located on HIV chromosome are gag, pol, env. The functions of gag, pol ...

- Why are mutations at D185, D186 and D110 are so detrimental to RT activity? (15 Points) Mutations at D185, D186 and D110 are very detrimental to RT activity owing to the fact that the three carboxylate residues have been documented to participate in some forms of physiological processes and metal coordination function that is fundamentally required in the binding of deoxyrobonucleotide substrates to the enzyme. And so, when these subunits are interfered as a result of mutation then the fore mentioned biological process are essentially incapacitated. Furthermore, the region was also subcloned due to mutagenesis hence the high ...

Description and challenges

Hepatitis C is a type of infection that is caused by a virus that attacks the human liver resulting in inflammation. The virus is called Hepatitis C virus (HCV). The infected people show less or no symptoms during its early stages of infection (Michael, 2014, p 1178). Hepatitis C virus is considered the most dangerous of the Hepatitis infections. The virus is transmitted through the contact with contaminated blood, mostly through needles that are shared through the use of illegal drugs. One challenge with Hepatitis is that, during its early stages, one cannot know if he is infected or not. This ...

While it remains debatable that money cannot buy happiness, money certainly can buy quality mental health medications and services. It also may buy a sense of feeling good about one’s self – or at least feeling better in comparison to poorer people. Living in poverty and living with a mental health issue are often comorbidities. Common mental disorders (CMD) such as major depression and anxiety are treatable only if a person suffering from these disorders is able to get access to mental health care. Sadly, this is not often the case for those living at the poverty level or homelessness, no matter ...

(Author)

Introduction of restriction enzymes Restriction enzymes are highly diverse set of enzymes in bacteria that are used to identify specific 4- to 8-bp sequences referred to as restriction sites and cleave DNA strands internally at this site. These enzymes protect the bacteria from foreign DNA molecules such as those of phages. Restriction enzymes identify specific nucleotide sequences to differentiate between the “domestic” and “foreign” DNA. It attaches to the “recognition site” and breaks both strands of the DNA (Kufe et al.). Restriction enzymes may include EcoRV, EcoRI, and HindIII. EcoRV belongs to the type II restriction/modification system ...

Overview

World Wide Advertising agency Inc. is a new company specializing in advertising. Currently, the company is hiring staff in its newly established locations New York and Los Angeles. WAI are yet to implement an IT strategy and once they do, all IT operations will be taken over by the IT department. WAI has approached me seeking a solution that describes, implement and configure core IT services within the new organization. WAI is not constrained by financial obligations and thus, require a solution that is best for their needs for the next two to three years. It is recognized that the company’ ...

Critiquing Quantitative and Qualitative Studies

Several research techniques are available all with the aim of achieving precise data or information or data about something. Quantitative technique, sometimes referred to as true science, involves the use of mathematical and statistical methods in the analysis and drawing useful information from a specific set of data (Davies, 2009). On the other hand, qualitative is a type of technique used to study behavior and habits portrayed by humans under different environments. The critique is aimed at juxtaposing the two techniques involved in the field of research with critical analysis of the two methods.

Compare and Contrast Information

Hand hygiene especially in health care setting ...

Microbiology laboratory report

Abstract Bacteriophages are intracellular parasitic viruses that infect bacteria to carry out their multiplication. During the lytic infection cycles, phages lyse the host cells forming a clear zone called plaque on the agar media. The experiment is aimed to measure the number of plaques created when the virus T4 infects the host bacteria and their genetic material integrates into the genetic material of the host cell. This happens because the E.coli becomes resistant to T4 bacteriophage. The T4 phage was diluted in a test tube and then E.coli bacteria was added in the tubes. The mixture was poured with soft ...

Introduction: Genetic mutations are associated with changes in the genomic sequence that are the main cause of diversity among organisms. The changes in genetic sequence can occur at any instance and are known to have different consequences. Mutations are often associated with a change that affects the nucleic acids in most organisms. Nucleic acids are considered as the building blocks of DNA. On the other hand, DNA are associated with the storage of information that is transferred to the offspring during reproduction. Mutations are associated with diversity and considered as an essential part in evolution. Genetic mutation is considered to ...

INTRODUCTION:

Canada is a friendly country that supports trading activities at its best, which is the reason Canada is recognized as a trading nation. Government of Canada has devoted abundant resources to foster trade within the country, as well as external trade. Moreover, government has carried successful negotiations of diverse trade contracts with different nations. In the intervening time, when government was just focusing on making external trade easy and possible, Canada has lost its strength over trade within the country (Pierce and Branch, 2013). Country continues to get engrossed in many internal trade barriers that created firm obstacles to carry trade ...

Under the current laws, copyrights do not necessarily prohibit all copying and replication of the original contents. It gives some exceptions under the fair use doctrine (US CODE). Such a situation has opened loopholes for illegal duplication in the name of fair duplication. The laws therefore, are not adequately formulated. It would be prudent if the doctrine of fair use is amended such that no duplication would be made without the express permission from the creator. The law alone may not be effective as it has failed with lesser penalties for the convicts of copyrights. The penalty of the ...

Introduction/background

Saccharomyces cerevisiae is an organism that can exist either as a singled-cell organism or as pseudomycelia. It is used in many scientific studies. It is commonly known as baker’s yeast. Saccharomyces cerevisiae is widely employed in scientific studies mainly due to the following reasons: it has a sequenced genome, it is easy to maintain in the lab, researchers can easily manipulate its genetics, and it grows rapidly. Saccharomyces cerevisiae can live with two genomes (diploid, n=32) or one genome (haploid, n=16). Consequently, the organism can undergo meiotic differentiation. In diploid phase, cells of the saccharomyces cerevisiae are more resistant to ...

ABSTRACT

CRM databases are created to aid organizations in managing their customers thereby increasing their revenue and profits. A central database of customers and contacts can help an organization drive forward sales to get higher returns on marketing activities. This paper describes the design of a customer relation management database for an auto part store. The store will document relationships between customers, salespeople, inventory, and products, through parameters such as orders and order lines among others. Using modeling tools such as ERD, a model of the auto part store CRM will be developed. The model encompasses the analytical and transactional components to ...

Introduction

In order to manage and supervise the operations of the entire company effectively, XYZ Company must consolidate the network infrastructure of the two long-distance sites, and build up one effective and secure network. Each site has its own server-controlled network operating on the Microsoft Windows Server technology. The Dallas site runs MS Windows 2012 Server, while the second site runs MS Windows 2008 Server. The fact that both sites are based on Microsoft Windows Server already gives XYZ Company a major advantage because the consolidation will mainly involve configurations based on the same network operating system. There may be ...

Introduction

Marburg virus disease (formerly known as Marburg hemorrhagic fever) is a severe zoonotic (animal-borne) disease, affecting both humans and non-primates. The source of infection for primates is unknown. However, research indicates that bats mainly infect the humans. The Ribonucleic acid (RNA) virus belongs to the filovirus family. Filoviruses belong to the order Mononegavirales. These viruses are enveloped, non-segmented, and negative-stranded. Marburg virus and Ebolavirus are the two genera of Filoviradae family. The only species in the genus Marburg virus is Lake Victoria margburg virus (Center for Food Security and Public Health, 2009, p.1). The virus has caused epidemics in ...

Introduction

In the mouse and other mammalian species, the pool of primordial follicles becomes established during fetal or neonatal life (Oktay et al., 1995). Over the mammal’s lifespan, the follicles undergo growth and development, and eventually the initial reserve of follicles begins to diminish during the mammal’s midlife. Briefly, follicular cells move from a primordial phase, in which little DNA synthesis is taking place, to enter a primary and then secondary stage, in which the granulose cells undergo intense proliferation and high levels of DNA synthesis can be observed. Antral and post- ovulation stages follow (Oktay et al., 1995). Folliculogenesis ...

Abstract:

DNA (Deoxyribonucleic acid) is hereditary material found in most organisms and carries the genetic information required to build and maintain a living organism. DNA was first discovered in the late 1800's, but it was not until scientists unraveled its structure in the 1950s that its importance in genetics and the whole field of biological sciences became realized. This paper assesses the structure, history and applications of DNA into solving real world problems in medicine, agriculture, biochemical research and forensics. DNA can replicate itself which ensures that genetic information and consequently biological traits can be passed on from one generation to ...

Introduction

Herpes Simplex virus type 2 (HSV-2) is a virus that belongs to the alpha herpes viridae subfamily and causes genital ulcer diseases. The transmission of HSV-2 occurs most often due to a sexual intercourse in humans, although it can disseminate through physical contact with the lesions and saliva from the patients. Medical professionals may contract the infection and lesions on their fingers, if they inadvertently contact the patient’s vaginal mucosa or mouth, without using appropriate gloves. The HSV-2 infection is known to be asymptomatic in 80 % of the cases . Genital herpes is a frequent infection acquired during pregnancy and about 5 % ...

Gmail is an email service that is provided by mogul company Google well known for its browser services Google provides several internet services in cloud computing that include; Google Calendar, Google App Engine, Google Docs, Google Cloud Storage, and Gmail among others. Foremost, the choice for Gmail as a mailing service for an institution such as a university presents several security advantages. Gmail employs user passwords to ensure the security of user accounts. The passwords are integrated into the browser information that is stored in the programs files of the primary disk C of the computer. What is more the password ...

Research Plan

Introduction Toxin-antitoxin (TA) systems incorporate pervasively in prokaryotic genomes that have also been suggested to perform a role in numerous critical cellular operations (Van, & Bast, 2009). These systems characteristically comprise of a two-gene operon encoding a toxic protein molecule which aims at an important cellular purpose and an antitoxin that connects to and hinders the toxin. Control of toxin action is attained via differential constancy of the stable toxin as well as the unstable antitoxin (Kamada & Hanaoka, 2005). In several occasions, the antitoxin also operates as a transcriptional autorepressor of the operon, whereby the degradation of the antitoxin leads to transcriptional introduction ...

Embryonic stem cell is a crucial factor in the developmental process of a multicellular organism. Embryonic stem cells (ESCs) are derived at early stages during development and eventually give rise to all type of tissues and organs in an animal. The ES cell lines have three properties consisting of self-renewal, primary chimera formation and pluripotency [1]. Pluripotency, a key feature of ESCs, refers to the capacity of a cell to differentiate into several different types of tissues [2]. An array of cellular factors play important role in maintaining pluripotency and determining cell fate in the developmental pathway. Negative effects on these factors may ...

Self-driving cars

Google has developed self-driving cars. Although the cars are not yet fully developed, they have been tested on the roads. The cars are manned by operators who understand how the technology works. The cars have been developed to make use of cameras, sensors that use sensor technology and laser range finders so that they are able to navigate the traffic. They have also been developed to make use of maps which are detailed. This way, they are able to know the traffic and the road that has been set ahead. This is enhanced and made possible with the well-developed ...

Introduction

Complexity and overwhelming nature of issues to be coped with in some countries of the world calls forth the need to add extra dimensions to state’s combating the issues in terms of implementing its functions, and change existing systems and institutions. Social entrepreneurship represents a process by which citizens can either create or transform institutions to advance solutions to such issues, as poverty, illnesses, environment pollution, corruption and human rights abuses (Bornstein&Davis, 2010, pp.1-2). One of world-known contemporary social entrepreneurs is Mohammad Yunus, founder and manager of Grameen bank and 2006 Noble prize winner, who is currently successfully ...

Innovations under conditions of uncertainty- Normative model of innovation

Introduction Innovation is one of the most important aspects in most of the business organizations as they strive to attain their goals and objectives. It brings about changes in the traditional way of management to new and improved methods. All these methods will try to answer questions that are usually presented to managers regarding the value of the products and services offered these organizations (Davis& Scott, 2007). The need for to coming up with characteristics that can stimulate innovations is paramount to organization’s success. Furthermore there is need to provide a conducive environment where such innovators can thrive ...

Most chemotherapy drugs are designed to block DNA replication; majority of the generally and successfully drugs are DNA-damaging agents. The DNA targeting has proven to result in comparatively potent and discerning distribution of cancerous cells. Compounds which are empirically identified with anticancer activity have been indicated to target DNA as the crow flies or through enzyme inhibition which controls the integrity of the DNA of offers the DNA building blocks. With the revelation of the DNA structure various therapeutic modlaities have been established namely; the antimetabolites which, depletes the nucleotides comprising folic acid, an example being methotrexate. Alkylation agents ...

WATER QUALITY AND CONTAMINATION REPORT

ABSTRACT The process of water filtration systems is to remove impurities from a water source to create potable water in sufficient quantities to supply a municipality. In order to do this water is filtered by several different processes to remove different types of impurities. To test the efficacy of these different processes, a series of laboratory experiments was set up using the same type of materials and processes, but on a smaller scale. The data suggests that these processes are effective in removing most impurities and contaminants, However there is room for improvement and a higher quality of drinking water could be obtained ...

The advancement of technology has precipitated a revolution in scientific understanding over the last several decades. Advancements in research tools has led to new insights into every facet of scientific discovery within the realms of chemistry, physics, and biology and all the sub-disciplines forming their constitution. Increased discovery has brought with it opportunities for cross discipline cooperation which has resulted in the formation of new disciplines and has galvanized scientists to press the boundaries of research and application as has never been seen in human history. One such field testing those limits is genetics. Today’s geneticists have expanded beyond ...

Abstract

IFITM3, a protein induced by interferon, restricts reovirus infection in host cells and inhibits the viral replication. It affects the proper penetration of the virus by altering the dynamics of the viral uncoating in the endosomes. This study is the first in characterizing the anti-viral activity of IFITM3 on non enveloped viruses that depend on endosome for cellular entry. Following contagion with a virus, the body triggers the release of a class of cytokines, interferons that are involved in first line of defense against infection. Type I interferons are specifically induced in the cells following insult with both DNA and RNA ...

Abstract

Researchers from the University of Washington and Fred Hutchinson Cancer Research published a study in Nature based to demonstrate the identification of immunological role of a class of cytotoxic T cells in genital herpes. They identified the cells to be CDT cells that primarily exist in the skin of genital region and mucosa. These cells inhibit the recurrence of genital herpes. Since they suppress the replication of the HSV-2 virus, at the site of recurrence they also prevent symptoms in the patient.

Genital herpes is a sexually transmitted disease affecting more than 24 million people in the US and 60-80 million ...

Through seamless exchange of information over the internet, security concerns have been raised. The three major information security areas authentication, authorization and confidentiality has been compromised via the internet through hacking, malware and spyware programs. For example, mishandled passwords or codes may lead to stealing of information from the computer systems which in essence has severe consequences in terms of individuals and the companies affected. The pharmacy can suffer from various security threats attributed to behavioral, infrastructural and physical attributes. In this paper, the focus lies on separating security vulnerabilities and discussing their solutions.

PHYSICAL VULNERABILITIES

Physical vulnerabilities affect the ...

Businesses use information technology to quickly and effectively process information. Employees use electronic mail and Voice Over Internet Protocol (VOIP) telephone systems to communicate. Electronic data interchange (EDI) is used to transmit data including orders and payments from one company to another. Servers process information and store large amounts of data. Desktop computers, laptops and wireless devices are used by employees to create, process, manage and communicate information. What do you when your information technology stops working? An information technology disaster recovery plan (IT DRP) should be developed in conjunction with the business continuity plan. Priorities and recovery ...